Who are High-dose epinephrine's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Ephedrine-S, Ephedrine, bolus, Atropine sulfate and epinephrine, cardiac output changes with "ephedrine", epinephrine perfusion, Racemic adrenaline.

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Last reviewed 2026-05-14 · How we verify

High-dose epinephrine — Competitive Intelligence Brief

High-dose epinephrine (High-dose epinephrine) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Catecholamine; adrenergic agonist. Area: Cardiovascular; Emergency Medicine.

marketed Catecholamine; adrenergic agonist Alpha-1, alpha-2, beta-1, and beta-2 adrenergic receptors Cardiovascular; Emergency Medicine Small molecule Live · refreshed every 30 min

Target snapshot

High-dose epinephrine (High-dose epinephrine) — Icahn School of Medicine at Mount Sinai. High-dose epinephrine is a catecholamine that acts as a non-selective adrenergic agonist, stimulating alpha and beta-adrenergic receptors to increase heart rate, blood pressure, and cardiac output.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
High-dose epinephrine TARGET	High-dose epinephrine	Icahn School of Medicine at Mount Sinai	marketed	Catecholamine; adrenergic agonist	Alpha-1, alpha-2, beta-1, and beta-2 adrenergic receptors
Ephedrine-S	Ephedrine-S	Dalian Municipal Central Hospital	marketed	Sympathomimetic amine	Alpha-1, alpha-2, beta-1, and beta-2 adrenergic receptors
Ephedrine, bolus	Ephedrine, bolus	University of Parma	marketed	Sympathomimetic amine; adrenergic agonist	Alpha-1, alpha-2, beta-1, and beta-2 adrenergic receptors
Atropine sulfate and epinephrine	Atropine sulfate and epinephrine	Dar El Oyoun Hospital	marketed	Anticholinergic agent and sympathomimetic amine combination	Muscarinic acetylcholine receptors (atropine); alpha-1, alpha-2, beta-1, and beta-2 adrenergic receptors (epinephrine)
cardiac output changes with "ephedrine"	cardiac output changes with "ephedrine"	University Tunis El Manar	marketed	Sympathomimetic amine	Alpha-1, alpha-2, beta-1, and beta-2 adrenergic receptors
epinephrine perfusion	epinephrine perfusion	Central Hospital, Nancy, France	marketed	Sympathomimetic amine / Catecholamine	Alpha-1, alpha-2, beta-1, and beta-2 adrenergic receptors
Racemic adrenaline	Racemic adrenaline	Oslo University Hospital	marketed	Sympathomimetic amine; adrenergic agonist	Alpha-1, alpha-2, beta-1, and beta-2 adrenergic receptors

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Catecholamine; adrenergic agonist class)

Kasr El Aini Hospital · 2 drugs in this class
Aga Khan University · 1 drug in this class
Icahn School of Medicine at Mount Sinai · 1 drug in this class
Ministry of Health, Spain · 1 drug in this class
University of Louisville · 1 drug in this class

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Cite this brief

Drug Landscape (2026). High-dose epinephrine — Competitive Intelligence Brief. https://druglandscape.com/ci/high-dose-epinephrine. Accessed 2026-05-14.

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