Exparel Injectable Product — Competitive Intelligence Brief

Exparel Injectable Product (Exparel Injectable Product) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic (liposomal formulation). Area: Pain Management / Anesthesia.

marketed Local anesthetic (liposomal formulation) Voltage-gated sodium channels Pain Management / Anesthesia Small molecule

Target snapshot

Exparel Injectable Product (Exparel Injectable Product) — Pacira Pharmaceuticals, Inc. Exparel is a liposomal formulation of bupivacaine that provides prolonged local anesthesia by slowly releasing the anesthetic agent over an extended period.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Exparel Injectable Product TARGET	Exparel Injectable Product	Pacira Pharmaceuticals, Inc	marketed	Local anesthetic (liposomal formulation)	Voltage-gated sodium channels
Oral Zonisamide Therapy	Oral Zonisamide Therapy	Affiliated Hospital of Nantong University	marketed	Anticonvulsant / Antiepileptic drug	Voltage-gated sodium channels, T-type calcium channels, carbonic anhydrase
oral suzetrigine	oral suzetrigine	University of Louisville	marketed	Selective sodium channel blocker	Voltage-gated sodium channels (Nav)
Bupivacaine 20cc	Bupivacaine 20cc	Hospital for Special Surgery, New York	marketed	Local anesthetic	Voltage-gated sodium channels
Bupivacaine Digital Block	Bupivacaine Digital Block	University of California, San Francisco	marketed	Local anesthetic	Voltage-gated sodium channels
Bupivacaine Hcl 0.5% Inj	Bupivacaine Hcl 0.5% Inj	Hospital for Special Surgery Florida	marketed	Local anesthetic	Voltage-gated sodium channels
Bupivacaine Injection [Marcaine]	Bupivacaine Injection [Marcaine]	South Egypt Cancer Institute	marketed	Local anesthetic	Voltage-gated sodium channels

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic (liposomal formulation) class)

1. Pacira Pharmaceuticals, Inc · 4 drugs in this class
2. Huazhong University of Science and Technology · 1 drug in this class
3. Maimonides Medical Center · 1 drug in this class
4. The Cleveland Clinic · 1 drug in this class
5. The Cooper Health System · 1 drug in this class
6. The University of Texas Health Science Center, Houston · 1 drug in this class
7. Tianjin Medical University General Hospital · 1 drug in this class
8. University of California, Davis · 1 drug in this class
9. Catherine Vandepitte, M.D. · 1 drug in this class
10. Wake Forest University Health Sciences · 1 drug in this class