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Ephedrine, bolus — Competitive Intelligence Brief
marketed
Sympathomimetic amine; adrenergic agonist
Alpha-1, alpha-2, beta-1, and beta-2 adrenergic receptors
Cardiovascular; Respiratory
Small molecule
Live · refreshed every 30 min
Target snapshot
Ephedrine, bolus (Ephedrine, bolus) — University of Parma. Ephedrine is a sympathomimetic amine that stimulates alpha and beta adrenergic receptors to increase heart rate, blood pressure, and bronchial airway dilation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Ephedrine, bolus TARGET | Ephedrine, bolus | University of Parma | marketed | Sympathomimetic amine; adrenergic agonist | Alpha-1, alpha-2, beta-1, and beta-2 adrenergic receptors | |
| epinephrine perfusion | epinephrine perfusion | Central Hospital, Nancy, France | marketed | Sympathomimetic amine / Catecholamine | Alpha-1, alpha-2, beta-1, and beta-2 adrenergic receptors | |
| Normal saline with epinephrine | Normal saline with epinephrine | West Penn Allegheny Health System | marketed | Sympathomimetic amine / Vasopressor | Alpha-1, alpha-2, beta-1, and beta-2 adrenergic receptors | |
| Low-dose epinephrine | Low-dose epinephrine | Icahn School of Medicine at Mount Sinai | marketed | Sympathomimetic amine / Catecholamine | Alpha-1, alpha-2, beta-1, and beta-2 adrenergic receptors | |
| cardiac output changes with "ephedrine" | cardiac output changes with "ephedrine" | University Tunis El Manar | marketed | Sympathomimetic amine | Alpha-1, alpha-2, beta-1, and beta-2 adrenergic receptors | |
| Ephedrine-S | Ephedrine-S | Dalian Municipal Central Hospital | marketed | Sympathomimetic amine | Alpha-1, alpha-2, beta-1, and beta-2 adrenergic receptors | |
| Epinephrine (Adrenaline) | Epinephrine (Adrenaline) | Aga Khan University | marketed | Catecholamine; adrenergic agonist | Alpha-1, alpha-2, beta-1, and beta-2 adrenergic receptors |
Recent regulatory actions (last 90 days)
- — cardiac output changes with "ephedrine" · FDA · approved · US · University Tunis El Manar
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Sympathomimetic amine; adrenergic agonist class)
- Oslo University Hospital · 1 drug in this class
- University Hospital, Ghent · 1 drug in this class
- University of Parma · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Ephedrine, bolus — Competitive Intelligence Brief. https://druglandscape.com/ci/ephedrine-bolus. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing