Chloroprocaine 3% eye gel — Competitive Intelligence Brief

Chloroprocaine 3% eye gel (Chloroprocaine 3% eye gel) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic (ester). Area: Ophthalmology.

phase 3 Local anesthetic (ester) Voltage-gated sodium channels Ophthalmology Small molecule

Target snapshot

Chloroprocaine 3% eye gel (Chloroprocaine 3% eye gel) — Sintetica SA. Chloroprocaine is a local anesthetic that blocks sodium channels in nerve cell membranes, preventing the initiation and conduction of nerve impulses in the eye.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Chloroprocaine 3% eye gel TARGET	Chloroprocaine 3% eye gel	Sintetica SA	phase 3	Local anesthetic (ester)	Voltage-gated sodium channels
Anesthetic Topical Adhesive Synera	Anesthetic Topical Adhesive Synera	Brown, Theodore R., M.D., MPH	marketed	Topical local anesthetic	Voltage-gated sodium channels
Topiramate monotherapy	Topiramate monotherapy	Johnson & Johnson Taiwan Ltd	marketed	Anticonvulsant / Antiepileptic agent	GABA-A receptor; voltage-gated sodium channels
Levobupivacaine 0,5%	Levobupivacaine 0,5%	ASST Gaetano Pini-CTO	marketed	Local anesthetic (amide)	Voltage-gated sodium channels
Liposome bupivacaine	Liposome bupivacaine	Catherine Vandepitte, M.D.	marketed	Local anesthetic (liposomal formulation)	Voltage-gated sodium channels
Intravenous Lidocaine infusion + Standard Anesthesia	Intravenous Lidocaine infusion + Standard Anesthesia	Instituto Mexicano del Seguro Social	marketed	Local anesthetic (sodium channel blocker)	Voltage-gated sodium channels
IV lignocaine bolus and infusion	IV lignocaine bolus and infusion	University of Auckland, New Zealand	marketed	Local anesthetic; Class IB antiarrhythmic agent	Voltage-gated sodium channels

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic (ester) class)

1. Sintetica SA · 4 drugs in this class
2. Centre Hospitalier Universitaire Saint Pierre · 1 drug in this class
3. Nova Scotia Health Authority · 1 drug in this class
4. American Genomics, LLC · 1 drug in this class
5. University of Miami · 1 drug in this class
6. Wenzhou Medical University · 1 drug in this class
7. Oregon Health and Science University · 1 drug in this class