Chlorhexidine gluconate at 2% — Competitive Intelligence Brief

Chlorhexidine gluconate at 2% (Chlorhexidine gluconate at 2%) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antimicrobial agent / Antiseptic. Area: Infectious Disease / Antisepsis.

phase 3 Antimicrobial agent / Antiseptic Bacterial cell membrane and proteins Infectious Disease / Antisepsis Small molecule

Target snapshot

Chlorhexidine gluconate at 2% (Chlorhexidine gluconate at 2%) — Universidad de Guanajuato. Chlorhexidine gluconate is a broad-spectrum antimicrobial agent that disrupts bacterial cell membranes and denatures proteins, leading to rapid bactericidal and bacteriostatic effects.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Chlorhexidine gluconate at 2% TARGET	Chlorhexidine gluconate at 2%	Universidad de Guanajuato	phase 3	Antimicrobial agent / Antiseptic	Bacterial cell membrane and proteins
Chlorhexidine 0.2% Mouthrinse	Chlorhexidine 0.2% Mouthrinse	University of Oslo	marketed	Antimicrobial agent / Antiseptic	Bacterial cell membrane and proteins
Chlorhexidine oral care	Chlorhexidine oral care	University of Pavia	marketed	Antimicrobial agent / Antiseptic	Bacterial cell membrane and proteins
Adapalene/Benzoyl Peroxide Gel 0.3-2.5%	Adapalene/Benzoyl Peroxide Gel 0.3-2.5%	Derm Research, PLLC	marketed	Retinoid + peroxide combination	Retinoic acid receptors (adapalene); bacterial cell membrane and proteins (benzoyl peroxide)
Adapalene/benzoyl peroxide gel, 0.1%/2.5%	Adapalene/benzoyl peroxide gel, 0.1%/2.5%	Galderma R&D	marketed	Retinoid + peroxide combination	Retinoic acid receptors (adapalene); bacterial cell membrane and proteins (benzoyl peroxide)
Chlorhexidine 0.06% mouthrinse	Chlorhexidine 0.06% mouthrinse	University of Oslo	marketed	Antimicrobial oral rinse	Bacterial cell membrane and proteins
adapalene/benzoyl peroxide	adapalene/benzoyl peroxide	Galderma R&D	marketed	Retinoid + peroxide combination	Retinoic acid receptors (adapalene); bacterial cell membrane and proteins (benzoyl peroxide)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antimicrobial agent / Antiseptic class)

1. Universidad de Guanajuato · 2 drugs in this class
2. University of Oslo · 2 drugs in this class
3. Johns Hopkins University · 1 drug in this class
4. The Cooper Health System · 1 drug in this class
5. Universidade Federal do Ceara · 1 drug in this class
6. University of Milan · 1 drug in this class
7. University of Pavia · 1 drug in this class
8. University of Pennsylvania · 1 drug in this class
9. University of Santiago de Compostela · 1 drug in this class
10. HaEmek Medical Center, Israel · 1 drug in this class