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Chlorhexidine gluconate at 2%

Universidad de Guanajuato · Phase 3 active Small molecule

Chlorhexidine gluconate at 2% is a Antimicrobial agent / Antiseptic Small molecule drug developed by Universidad de Guanajuato. It is currently in Phase 3 development for Oral antimicrobial rinse for plaque and gingivitis prevention, Topical antiseptic for wound irrigation and skin antisepsis, Oral care in immunocompromised patients.

Chlorhexidine gluconate is a broad-spectrum antimicrobial agent that disrupts bacterial cell membranes and denatures proteins, leading to rapid bactericidal and bacteriostatic effects.

Chlorhexidine gluconate is a broad-spectrum antimicrobial agent that disrupts bacterial cell membranes and denatures proteins, leading to rapid bactericidal and bacteriostatic effects. Used for Oral antimicrobial rinse for plaque and gingivitis prevention, Topical antiseptic for wound irrigation and skin antisepsis, Oral care in immunocompromised patients.

At a glance

Generic nameChlorhexidine gluconate at 2%
SponsorUniversidad de Guanajuato
Drug classAntimicrobial agent / Antiseptic
TargetBacterial cell membrane and proteins
ModalitySmall molecule
Therapeutic areaInfectious Disease / Antisepsis
PhasePhase 3

Mechanism of action

Chlorhexidine is a cationic biguanide that binds to negatively charged bacterial cell membranes, causing leakage of cellular contents and protein denaturation. At 2% concentration, it exhibits potent activity against a wide range of gram-positive and gram-negative bacteria, as well as some fungi and viruses. It is commonly used as a topical antiseptic and antimicrobial rinse.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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Frequently asked questions about Chlorhexidine gluconate at 2%

What is Chlorhexidine gluconate at 2%?

Chlorhexidine gluconate at 2% is a Antimicrobial agent / Antiseptic drug developed by Universidad de Guanajuato, indicated for Oral antimicrobial rinse for plaque and gingivitis prevention, Topical antiseptic for wound irrigation and skin antisepsis, Oral care in immunocompromised patients.

How does Chlorhexidine gluconate at 2% work?

Chlorhexidine gluconate is a broad-spectrum antimicrobial agent that disrupts bacterial cell membranes and denatures proteins, leading to rapid bactericidal and bacteriostatic effects.

What is Chlorhexidine gluconate at 2% used for?

Chlorhexidine gluconate at 2% is indicated for Oral antimicrobial rinse for plaque and gingivitis prevention, Topical antiseptic for wound irrigation and skin antisepsis, Oral care in immunocompromised patients.

Who makes Chlorhexidine gluconate at 2%?

Chlorhexidine gluconate at 2% is developed by Universidad de Guanajuato (see full Universidad de Guanajuato pipeline at /company/universidad-de-guanajuato).

What drug class is Chlorhexidine gluconate at 2% in?

Chlorhexidine gluconate at 2% belongs to the Antimicrobial agent / Antiseptic class. See all Antimicrobial agent / Antiseptic drugs at /class/antimicrobial-agent-antiseptic.

What development phase is Chlorhexidine gluconate at 2% in?

Chlorhexidine gluconate at 2% is in Phase 3.

What are the side effects of Chlorhexidine gluconate at 2%?

Common side effects of Chlorhexidine gluconate at 2% include Tooth staining, Taste alteration, Oral irritation, Allergic contact dermatitis.

What does Chlorhexidine gluconate at 2% target?

Chlorhexidine gluconate at 2% targets Bacterial cell membrane and proteins and is a Antimicrobial agent / Antiseptic.

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