Bupivacaine FNB — Competitive Intelligence Brief

Bupivacaine FNB (Bupivacaine FNB) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic. Area: Pain Management / Regional Anesthesia.

marketed Local anesthetic Voltage-gated sodium channels Pain Management / Regional Anesthesia Small molecule

Target snapshot

Bupivacaine FNB (Bupivacaine FNB) — Pacira Pharmaceuticals, Inc. Bupivacaine is a local anesthetic that blocks sodium channels in nerve fibers, preventing the initiation and conduction of nerve impulses.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Bupivacaine FNB TARGET	Bupivacaine FNB	Pacira Pharmaceuticals, Inc	marketed	Local anesthetic	Voltage-gated sodium channels
Liposome bupivacaine	Liposome bupivacaine	Catherine Vandepitte, M.D.	marketed	Local anesthetic (liposomal formulation)	Voltage-gated sodium channels
IV lignocaine bolus and infusion	IV lignocaine bolus and infusion	University of Auckland, New Zealand	marketed	Local anesthetic; Class IB antiarrhythmic agent	Voltage-gated sodium channels
Intravenous Lidocaine infusion + Standard Anesthesia	Intravenous Lidocaine infusion + Standard Anesthesia	Instituto Mexicano del Seguro Social	marketed	Local anesthetic (sodium channel blocker)	Voltage-gated sodium channels
Infiltration - EXPAREL	Infiltration - EXPAREL	Pacira Pharmaceuticals, Inc	marketed	Long-acting local anesthetic	Voltage-gated sodium channels
Anesthetics, Local	Anesthetics, Local	University of Alberta	marketed	Local anesthetic	Voltage-gated sodium channels
Levobupivacaine and Fentanyl	Levobupivacaine and Fentanyl	Hamad Medical Corporation	marketed	Local anesthetic with opioid analgesic combination	Voltage-gated sodium channels; mu-opioid receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic class)

1. University of California, San Diego · 3 drugs in this class
2. Durect · 3 drugs in this class
3. Pacira Pharmaceuticals, Inc · 3 drugs in this class
4. Wake Forest University Health Sciences · 3 drugs in this class
5. Medical University of Vienna · 3 drugs in this class
6. Imperial College London · 2 drugs in this class
7. Hvidovre University Hospital · 2 drugs in this class
8. Innocoll · 2 drugs in this class
9. George Washington University · 2 drugs in this class
10. Guy's and St Thomas' NHS Foundation Trust · 2 drugs in this class