Bupivacaine alone — Competitive Intelligence Brief

Bupivacaine alone (Bupivacaine alone) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic (amide). Area: Anesthesia.

marketed Local anesthetic (amide) Voltage-gated sodium channels Anesthesia Small molecule

Target snapshot

Bupivacaine alone (Bupivacaine alone) — The University of Texas Health Science Center, Houston. Bupivacaine is a local anesthetic that blocks sodium channels in nerve cell membranes, preventing the initiation and conduction of nerve impulses.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Bupivacaine alone TARGET	Bupivacaine alone	The University of Texas Health Science Center, Houston	marketed	Local anesthetic (amide)	Voltage-gated sodium channels
Ropivacaine + saline solution	Ropivacaine + saline solution	Federal University of Minas Gerais	marketed	Local anesthetic (amide class)	Voltage-gated sodium channels
Ropivacaine + dexamethasone	Ropivacaine + dexamethasone	Sahiwal medical college sahiwal	marketed	Local anesthetic with corticosteroid adjuvant	Voltage-gated sodium channels; glucocorticoid receptor
Ropivacaine Monohydrochloride	Ropivacaine Monohydrochloride	Clinique Saint-Jean, Bruxelles	marketed	Local anesthetic (amide class)	Voltage-gated sodium channels
Triamcinolone + Lidocaine	Triamcinolone + Lidocaine	MetroHealth Medical Center	marketed	Corticosteroid + Local anesthetic combination	Glucocorticoid receptor (triamcinolone); voltage-gated sodium channels (lidocaine)
TAP block with Bupivacaine at 0.25%	TAP block with Bupivacaine at 0.25%	Patricia Salazar Villegas	marketed	Local anesthetic	Voltage-gated sodium channels
Ropivacaine with NaCl	Ropivacaine with NaCl	Corewell Health East	marketed	Local anesthetic	Voltage-gated sodium channels

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic (amide) class)

1. Poznan University of Medical Sciences · 4 drugs in this class
2. Nantes University Hospital · 3 drugs in this class
3. Bozyaka Training and Research Hospital · 2 drugs in this class
4. ASST Gaetano Pini-CTO · 2 drugs in this class
5. Centre Hospitalier Universitaire de Nīmes · 1 drug in this class
6. Chiang Mai University · 1 drug in this class
7. Beijing Tiantan Hospital · 1 drug in this class
8. Complejo Hospitalario Universitario de Granada · 1 drug in this class
9. Ciusss de L'Est de l'Île de Montréal · 1 drug in this class
10. China Medical University, China · 1 drug in this class