Bupivacaine 0.5% , Dexamethasone — Competitive Intelligence Brief

Bupivacaine 0.5% , Dexamethasone (Bupivacaine 0.5% , Dexamethasone) competitive landscape: 5 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Local anesthetic with corticosteroid adjuvant. Area: Anesthesia and Pain Management.

marketed Local anesthetic with corticosteroid adjuvant Voltage-gated sodium channels (bupivacaine); glucocorticoid receptor (dexamethasone) Anesthesia and Pain Management Small molecule

Target snapshot

Bupivacaine 0.5% , Dexamethasone (Bupivacaine 0.5% , Dexamethasone) — Sisli Hamidiye Etfal Training and Research Hospital. Bupivacaine blocks sodium channels to provide local anesthesia, while dexamethasone reduces inflammation and swelling at the injection site.

Comparator set (5 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Bupivacaine 0.5% , Dexamethasone TARGET	Bupivacaine 0.5% , Dexamethasone	Sisli Hamidiye Etfal Training and Research Hospital	marketed	Local anesthetic with corticosteroid adjuvant	Voltage-gated sodium channels (bupivacaine); glucocorticoid receptor (dexamethasone)
Bupivacaine and Dexamethasone Injection	Bupivacaine and Dexamethasone Injection	Colette Curtis MD	marketed	Local anesthetic with corticosteroid adjuvant	Voltage-gated sodium channels (bupivacaine); glucocorticoid receptor (dexamethasone)
Ropivacaine + dexamethasone	Ropivacaine + dexamethasone	Sahiwal medical college sahiwal	marketed	Local anesthetic with corticosteroid adjuvant	Voltage-gated sodium channels; glucocorticoid receptor
Bupivacaine Hydrochloride combined with dexamethasone	Bupivacaine Hydrochloride combined with dexamethasone	Zhejiang Cancer Hospital	marketed	Local anesthetic with corticosteroid adjuvant	Voltage-gated sodium channels (bupivacaine); glucocorticoid receptor (dexamethasone)
Ropivacaine and dexamethasone	Ropivacaine and dexamethasone	University of Texas Southwestern Medical Center	phase 3	Local anesthetic with corticosteroid adjuvant	Voltage-gated sodium channels; glucocorticoid receptor
Ropivacaine 0.2% + Dexamethasone	Ropivacaine 0.2% + Dexamethasone	Instituto do Coracao	phase 3	Local anesthetic with corticosteroid adjuvant	Voltage-gated sodium channels (ropivacaine); glucocorticoid receptor (dexamethasone)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Local anesthetic with corticosteroid adjuvant class)

1. Colette Curtis MD · 1 drug in this class
2. Instituto do Coracao · 1 drug in this class
3. Sahiwal medical college sahiwal · 1 drug in this class
4. Sisli Hamidiye Etfal Training and Research Hospital · 1 drug in this class
5. University of Texas Southwestern Medical Center · 1 drug in this class
6. Zhejiang Cancer Hospital · 1 drug in this class