NCT04095845 is a NA clinical trial of CO THA in Osteoarthritis, Hip, sponsored by University College, London.

Who is sponsoring NCT04095845?

NCT04095845 is sponsored by University College, London.

What drugs are being tested in NCT04095845?

Interventions in NCT04095845: CO THA, Mako THA.

What condition does NCT04095845 study?

NCT04095845 studies Osteoarthritis, Hip, Osteoarthritis, Surgery.

Is NCT04095845 still recruiting?

NCT04095845 is currently completed. Last updated 9 July 2025.

Last reviewed 2025-07-09 · How we verify

NCT04095845

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Conventional Total Hip Arthroplasty vs Mako Robotic-arm Assisted Total Hip Arthroplasty

Completed NA Last updated 9 July 2025

What this trial tests

NA trial testing CO THA in Osteoarthritis, Hip in 60 participants. Completed in 31 October 2024.

Timeline

9 November 2018

Primary endpoint
30 September 2024

31 October 2024

Quick facts

Lead sponsor	University College, London
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	60
Start date	9 November 2018
Primary completion	30 September 2024
Estimated completion	31 October 2024
Sites	1 location across United Kingdom

Drugs / interventions tested

CO THA
Mako THA

Conditions studied

Osteoarthritis, Hip — all drugs for Osteoarthritis, Hip →
Osteoarthritis — all drugs for Osteoarthritis →
Surgery — all drugs for Surgery →

Sponsor

University College, London

Who can join

Adults 18 to 80, any sex, with Osteoarthritis, Hip or Osteoarthritis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The overall aim of this single-centre, prospective randomised controlled trial is to compare clinical, functional, and radiological outcomes in CO THA versus Mako THA. Patients undergoing Mako THA will form the investigation group and those undergoing CO THA will form the control group.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Computerised tomography-based planning with conventional total hip arthroplasty versus robotic-arm assisted total hip arthroplasty: study protocol for a prospective randomised controlled trial.
Kayani B, Konan S, Tahmassebi J, Ayuob A, et al · · 2020 · cited 3× · PMID 32912292 · DOI 10.1186/s13063-020-04702-7

Verify or expand the search:

Other recruiting trials for Osteoarthritis, Hip

Currently open trials in the same condition.

NCT07386561 — Virtual Reality Therapy and Non-Sleep Deep Rest Relaxation After Joint Arthroplasty · NA · active not recruiting
NCT06578182 — The Effect of ColcHicine on the Incidence of Knee or Hip Replacements · Phase 3 · recruiting
NCT06342843 — Direct Superior Approach Versus PosteroLateral Approach in Total Hip Arthroplasty (SPLAsH) · NA · recruiting
NCT06249958 — Transforming Rehabilitation: Personalised Care for a Better Quality of Life · recruiting
NCT05700682 — Perfusion MRI-targeted Joint Embolization for Chronic Musculoskeletal Pain of the Shoulder, Hip and Knee · recruiting

Other University College, London trials

Trials by the same sponsor.

NCT07386652 — Intensive Comprehensive Aphasia Programme for People With Post-Stroke Aphasia · NA · not yet recruiting
NCT06924086 — The Children's Adaptive Deep Brain Stimulation for Epilepsy Trial · NA · recruiting
NCT07386678 — Study of Imaging and Molecular Biomarkers in Uncomplicated Rhegmatogenous Retinal Detachment · not yet recruiting
NCT07414940 — ACTinium in Castrate-RESistant Prostate Cancer After LUTEtium · Phase 1, PHASE2 · not yet recruiting
NCT07214454 — TCDS for the Treatment of Chronic Migraine · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04095845 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University College, London
Last refreshed: 9 July 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04095845.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing