penicillin-binding proteins — Drug Target

All drugs that target penicillin-binding proteins — marketed and clinical-stage. Includes 5 drug classes acting on this target.

Drug classes

beta-lactam antibiotic · Beta-lactam antibiotic · Penicillin antibiotic · carbapenem antibiotic · Cephalosporin antibiotic

Marketed (2)

• Pseudomonas aeruginosa · Qilu Hospital of Shandong University · beta-lactam antibiotic · Infectious disease
  Pseudomonas aeruginosa is a broad-spectrum antibiotic that targets bacterial cell wall synthesis.
• Concomitant therapy 10 days · Incheon St.Mary's Hospital · Beta-lactam antibiotic · Infectious diseases
  This drug is used to treat various infections by inhibiting the bacterial cell wall synthesis.

Phase 3 pipeline (4)

• amoxicillin or moxifloxacin · Centre Hospitalier Universitaire de Nice · Penicillin antibiotic · Infectious diseases
  Amoxicillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.
• Usual antibiotic treatment · Assistance Publique - Hôpitaux de Paris · Beta-lactam antibiotic · Infectious disease
  This drug inhibits bacterial cell wall synthesis.
• meropenem (active comparator) · Pfizer · carbapenem antibiotic · Infectious Diseases
  Meropenem is a carbapenem antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.
• Standard Antibiotics treatment duration · University of Oxford · Beta-lactam antibiotic · Infectious diseases
  Standard antibiotics target and kill bacteria by inhibiting their cell wall synthesis or interfering with their protein synthesis.

Phase 2 pipeline (2)

• Cefuroxime Axetil Dispersible Tablets · Jiangsu Famous Medical Technology Co., Ltd. · Cephalosporin antibiotic · Infectious Disease
  Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.
• Beta Lactam Antibiotics · Esraa Salah Mohamed Abdallah Eladl · Beta-lactam antibiotic · Infectious Disease
  Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.

Phase 1 pipeline (3)

• Amoxicillin - high dose dual therapy · Unidade Local de Saúde do Alto Ave, EPE · Beta-lactam antibiotic · Infectious Disease
  Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.
• Amoxicillin healing phase · Belén Retamal-Valdes · Beta-lactam antibiotic · Infectious Disease
  Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.
• Amoxicillin during SRP · Belén Retamal-Valdes · Penicillin antibiotic · Infectious Disease
  Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.