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Amoxicillin - high dose dual therapy
Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.
Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. Used for Bacterial infections.
At a glance
| Generic name | Amoxicillin - high dose dual therapy |
|---|---|
| Sponsor | Unidade Local de Saúde do Alto Ave, EPE |
| Drug class | Beta-lactam antibiotic |
| Target | Penicillin-binding proteins |
| Modality | Small molecule |
| Therapeutic area | Infectious Disease |
| Phase | Phase 1 |
Mechanism of action
Amoxicillin is a beta-lactam antibiotic that works by inhibiting the synthesis of the bacterial cell wall, ultimately leading to cell lysis and death.
Approved indications
- Bacterial infections
Common side effects
- Diarrhea
- Nausea
- Vomiting
- Abdominal pain
- Allergic reactions
Key clinical trials
- 7-day High-Dose Vonoprazan-amoxicillin Dual Therapy Versus 14-day Vonoprazan-amoxicillin Dual Therapy for H. Pylori (NA)
- Optimization of Keverprazan-amoxicillin Dual Therapy for Eradicating Helicobacter Pylori Infection (PHASE3)
- 7-Day Vonoprazan, High-Dose Amoxicillin, and Bismuth Therapy (PHASE4)
- Efficacies of Susceptibility-guided vs Empiric Therapy for Rescue Treatment of Helicobacter Pylori Infection (PHASE4)
- Huazhi Rougan Granule as an Add-On Therapy for H. Pylori Infection With Metabolic-associated Steatohepatitis (NA)
- Effects of High-dose Dual Therapy and Bismuth Quadruple Therapy for Helicobacter Pylori Eradication on Intestinal Microecology (PHASE4)
- The Effects of High-dose Dual Therapy With Probiotics on Gut Microbiota for Helicobacter Pylori Rescue Treatment (NA)
- Efficacies of HDDT With or Without Bismuth vs Amoxicillin-metronidazole BQT for First-line H Pylori Eradication (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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