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NCT06292546
The Effects of High-dose Dual Therapy With Probiotics on Gut Microbiota for Helicobacter Pylori Rescue Treatment
NA trial testing Vonoprazan in Gut Microbiota in 72 participants. Completed in 28 February 2025.
30 December 2024
Quick facts
| Lead sponsor | Zhongshan Hospital (Xiamen), Fudan University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 72 |
| Start date | 31 January 2024 |
| Primary completion | 30 December 2024 |
| Estimated completion | 28 February 2025 |
| Sites | 1 location across China |
Drugs / interventions tested
- Vonoprazan — full drug profile →
- Amoxicillin (amoxicillin) — full drug profile →
- Bacillus subtilis enteric-coated capsules — full drug profile →
Conditions studied
- Gut Microbiota — all drugs for Gut Microbiota →
- Metabolic Disturbance — all drugs for Metabolic Disturbance →
- Helicobacter Pylori Eradication — all drugs for Helicobacter Pylori Eradication →
Sponsor
Zhongshan Hospital (Xiamen), Fudan University
Who can join
Adults 18 to 65, any sex, with Gut Microbiota or Metabolic Disturbance. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study was to evaluate the effects of High-dose Dual therapy combined with probiotics on the gut microbiota for Helicobacter pylori rescue treatment.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06292546
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Vonoprazan
Trials testing the same drug.
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- NCT06955520 — Vonaprazan Versus Esomeprazole for Healing of LA Grade B or Higher Esophagitis After POEM · NA · recruiting
- NCT07068607 — Efficacy Comparison of Vonoprazan Combined With Different Antibiotics in Dual Therapy for Helicobacter Pylori Eradicatio · Phase 4 · recruiting
- NCT07242456 — Head-to-head Study of Tegoprazan 50 mg BID Plus Amoxicillin 1 g TID vs. Vonoprazan 20 mg BID Plus Amoxicillin 1 g TID fo · Phase 2, PHASE3 · recruiting
- NCT06811207 — Comparison of the Efficacies of Two Novel Dose Dual Therapies in the First-line Helicobacter Pylori Eradication · Phase 3 · unknown
Other recruiting trials for Gut Microbiota
Currently open trials in the same condition.
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- NCT07214428 — Effects of Grape Powder on Psychological Distress and Gut Microbiota in College Students · NA · active not recruiting
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- NCT06935435 — Effects of Distinct Nebraska-Dry Bean Market Classes on Gut Microbiota · NA · active not recruiting
- NCT06854536 — A Study on the Changes and Prognosis of Intestinal Microbiota and Function in Infants With Food Allergies · active not recruiting
Other Zhongshan Hospital (Xiamen), Fudan University trials
Trials by the same sponsor.
- NCT06977841 — Tegoprazan-Based Therapies for H. Pylori Eradication: A Randomized Controlled Trial · NA · completed
- NCT06585176 — Epidemiological Studies and Risk Factor Analysis of GERD in Xiamen City · completed
- NCT07122284 — Gut Microbiome-Metabolome Profiling in H. Pylori-SIBO Comorbidity · completed
- NCT06293287 — Enoxaparin for Preventing the Radical Artery Occlusion After the Transradial Access Hepatic Arterial Infusion Chemothera · Phase 2 · unknown
- NCT05721300 — Study on Screening, Verification and Intervention of High-risk Patients With Liver Cancer · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06292546 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Zhongshan Hospital (Xiamen), Fudan University
- Last refreshed: 13 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06292546.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing