Cephalosporin antibiotic and beta-lactamase inhibitor combination

This page covers all Cephalosporin antibiotic and beta-lactamase inhibitor combination drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Bacterial cell wall synthesis, Penicillin-binding proteins (PBPs), Alpha-synuclein, D-amino-acid oxidase, Penicillin-binding protein 1A.

Targets

Bacterial cell wall synthesis · Penicillin-binding proteins (PBPs) · Alpha-synuclein, D-amino-acid oxidase, Penicillin-binding protein 1A · Penicillin-binding protein 1B · Penicillin-binding proteins

Marketed (3)

• Zavicefta, Ceftazidime-Avibactam · Pfizer · Infectious Disease · 638
• CREXONT ER · Impax Laboratories, LLC · Infectious Disease
  CREXONT ER is an extended-release formulation of cephalexin, a first-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.
• Rocephin · Generic (originally Roche) · Immunology

Phase 3 pipeline (3)

• Usual Cefepime Infusion · Hospital de Clinicas de Porto Alegre · Infectious diseases
  Cefepime is a fourth-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis.
• ceftriaxone 1gm for intravenous infusion · Ain Shams Maternity Hospital · Infectious disease
  Ceftriaxone works by inhibiting bacterial cell wall synthesis through inhibition of the enzyme penicillin-binding protein 1B.
• Prolonged Cefepime Infusion · Hospital de Clinicas de Porto Alegre · Infectious diseases
  Cefepime is a fourth-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis.

Phase 2 pipeline (2)

• Cefuroxime Axetil Dispersible Tablets · Jiangsu Famous Medical Technology Co., Ltd. · Infectious Disease
  Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.
• Ceftazidime or meropenem · Arrevus Inc. · Infectious disease
  Ceftazidime and meropenem are broad-spectrum cephalosporin antibiotics that inhibit bacterial cell wall synthesis.