Carbapenem antibiotic

This page covers all Carbapenem antibiotic drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Penicillin-binding proteins (PBPs), Bacterial penicillin-binding proteins; serine beta-lactamases, Penicillin-binding proteins (PBPs); beta-lactamase inhibition.

Targets

Penicillin-binding proteins (PBPs) · Bacterial penicillin-binding proteins; serine beta-lactamases · Penicillin-binding proteins (PBPs); beta-lactamase inhibition · penicillin-binding proteins (PBPs) · bacterial cell wall synthesis · penicillin-binding proteins · transpeptidase

Marketed (6)

• Meropenem Injection · Institute of Liver and Biliary Sciences, India · Infectious Disease
  Meropenem is a broad-spectrum beta-lactam antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.
• Meropenem Infusion · Unity Health Toronto · Infectious Disease
  Meropenem is a broad-spectrum beta-lactam antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.
• Imipenem/Cilastatin/Relebactam · Evopoint Biosciences Inc. · Infectious Disease
  Imipenem/cilastatin/relebactam is a combination of a broad-spectrum beta-lactam antibiotic, a renal dehydropeptidase inhibitor, and a beta-lactamase inhibitor that together kill bacteria by inhibiting cell wall synthesis while protecting against enzymatic degradation.
• Imipenem, Cilastatin and Relebactam · Joseph L. Kuti, PharmD · Infectious Disease
  Imipenem inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, cilastatin protects imipenem from renal degradation, and relebactam is a beta-lactamase inhibitor that prevents bacterial resistance.
• Maintaining carbapenem therapy · Assistance Publique - Hôpitaux de Paris · Infectious Disease
  Carbapenem antibiotics inhibit bacterial cell wall synthesis by binding to penicillin-binding proteins and disrupting peptidoglycan cross-linking.
• High-dose meropenem · National University of Singapore · Infectious Disease
  High-dose meropenem is a broad-spectrum beta-lactam antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.

Phase 3 pipeline (8)

• MEROPENEM 2 grams TID · BioVersys SAS · Infectious Disease
  Meropenem is a broad-spectrum beta-lactam antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.
• Meropenem for Injection · Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · Infectious Disease
  Meropenem is a broad-spectrum beta-lactam antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.
• Infex 200 IR · Neutec Ar-Ge San ve Tic A.Ş · Infectious diseases
  Infex 200 IR is an antibiotic that works by inhibiting bacterial cell wall synthesis.
• ertapenem sodium (MK0826) · Merck Sharp & Dohme LLC · Infectious Diseases
  Ertapenem sodium is a carbapenem antibiotic that inhibits bacterial cell wall synthesis.
• Sulopenem Etzadroxil/Probenecid · Iterum Therapeutics, International Limited · Infectious Diseases
  Sulopenem etzadroxil/probenecid is a combination antibiotic that works by inhibiting bacterial cell wall synthesis and reducing the reabsorption of the antibiotic in the kidneys.
• meropenem (active comparator) · Pfizer · Infectious Diseases
  Meropenem is a carbapenem antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.
• Meropenem intravenous · Fundación Pública Andaluza para la gestión de la Investigación en Sevilla · Infectious Disease
  Meropenem is a broad-spectrum beta-lactam antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.
• Ertapenem intravenous · Bayer · Infectious Disease
  Ertapenem is a broad-spectrum beta-lactam antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.

Phase 2 pipeline (1)

• ADL5859 · Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) · Infectious Diseases
  ADL5859 is a small molecule antibiotic that targets the bacterial cell wall synthesis.