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Ertapenem intravenous

Bayer · Phase 3 active Small molecule

Ertapenem is a broad-spectrum beta-lactam antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.

Ertapenem is a broad-spectrum beta-lactam antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. Used for Complicated intra-abdominal infections, Complicated skin and soft tissue infections, Community-acquired pneumonia.

At a glance

Generic nameErtapenem intravenous
SponsorBayer
Drug classCarbapenem antibiotic
TargetPenicillin-binding proteins (PBPs)
ModalitySmall molecule
Therapeutic areaInfectious Disease
PhasePhase 3

Mechanism of action

Ertapenem is a carbapenem antibiotic that penetrates bacterial cell walls and binds to penicillin-binding proteins, inhibiting cross-linking of peptidoglycan and leading to cell wall disruption and bacterial death. It has activity against a wide range of gram-positive, gram-negative, and anaerobic bacteria, making it useful for treating complicated intra-abdominal infections, complicated skin infections, and other serious bacterial infections.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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