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MEROPENEM 2 grams TID
Meropenem is a broad-spectrum beta-lactam antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.
Meropenem is a broad-spectrum beta-lactam antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. Used for Bacterial infections (specific indication under investigation by BioVersys SAS in Phase 3).
At a glance
| Generic name | MEROPENEM 2 grams TID |
|---|---|
| Also known as | Merrem |
| Sponsor | BioVersys SAS |
| Drug class | Carbapenem antibiotic |
| Target | Penicillin-binding proteins (PBPs) |
| Modality | Small molecule |
| Therapeutic area | Infectious Disease |
| Phase | Phase 3 |
Mechanism of action
Meropenem is a carbapenem antibiotic that penetrates bacterial cell walls and binds to penicillin-binding proteins, inhibiting cross-linking of peptidoglycan and causing cell wall degradation. This leads to bacterial cell lysis and death. It has activity against a wide range of gram-positive, gram-negative, and anaerobic bacteria.
Approved indications
- Bacterial infections (specific indication under investigation by BioVersys SAS in Phase 3)
Common side effects
- Diarrhea
- Nausea
- Headache
- Phlebitis at injection site
- Seizures
- Hypersensitivity reactions
Key clinical trials
- Efficacy and Safety of BV100 Plus Low Dose Polymyxin B Versus Colistin Plus High-dose Ampicillin/Sulbactam in Patients With Hospital-acquired or Ventilator-associated Bacterial Pneumonia Due to Carbapenem-resistant Acinetobacter Baumannii-calcoaceticus Complex (PHASE3)
- PipEracillin Tazobactam Versus mERoPENem for Treatment of Bloodstream Infections Caused by Cephalosporin-resistant Enterobacteriaceae (PETERPEN) (PHASE4)
- PipEracillin/Tazobactam Versus mERoPENem for Treatment of AmpC Producing Blood Stream Infections (PHASE4)
- A Pilot Study for Optimizing Meropenem Administration in the ICU (NA)
- Early Bactericidal Activity of Rifampin + Meropenem + Amoxicillin/Clavulanate in Adults With Pulmonary TB (PHASE2)
- Ceftolozane-tazobactam Versus Meropenem for ESBL and AmpC-producing Enterobacterales Bloodstream Infection (PHASE3)
- The Effect of Colistin Inhalation on Ventilator Associated Pneumonia (PHASE2, PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- MEROPENEM 2 grams TID CI brief — competitive landscape report
- MEROPENEM 2 grams TID updates RSS · CI watch RSS
- BioVersys SAS portfolio CI