Beta-lactam antibiotic

This page covers all Beta-lactam antibiotic drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Cell-wall peptidoglycan biosynthesis, Penicillin-binding proteins (PBPs); bacterial cell wall peptidoglycan, Penicillin-binding proteins (PBPs).

Targets

Cell-wall peptidoglycan biosynthesis · Penicillin-binding proteins (PBPs); bacterial cell wall peptidoglycan · Penicillin-binding proteins (PBPs) · Penicillin-binding proteins · penicillin-binding proteins · bacterial cell wall synthesis

Marketed (9)

• Bicillin C-R · Pfizer
  Penicillin G inhibits bacterial cell-wall peptidoglycan biosynthesis, rendering the cell wall osmotically unstable.
• Bicillin C-R · Pfizer
  Penicillin G inhibits bacterial cell-wall peptidoglycan biosynthesis, rendering the cell wall osmotically unstable.
• Beta-lactam antibiotic · University Hospital, Ghent · Infectious Disease
  Beta-lactam antibiotics inhibit bacterial cell wall synthesis by binding to penicillin-binding proteins and blocking peptidoglycan cross-linking.
• Benzathine penicillin G · International Maternal Pediatric Adolescent AIDS Clinical Trials Group · Infectious Disease
  Benzathine penicillin G inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins and blocking peptidoglycan cross-linking.
• Concomitant therapy 10 days · Incheon St.Mary's Hospital · Infectious diseases
  This drug is used to treat various infections by inhibiting the bacterial cell wall synthesis.
• Bicillin C-R · Pfizer Inc. · Metabolic
  Penicillin G inhibits bacterial cell-wall peptidoglycan biosynthesis, rendering the cell wall osmotically unstable.
• Pseudomonas aeruginosa · Qilu Hospital of Shandong University · Infectious disease
  Pseudomonas aeruginosa is a broad-spectrum antibiotic that targets bacterial cell wall synthesis.
• Amoxicillin (ST14) · National Taiwan University Hospital · Infectious Disease
  Amoxicillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins and blocking peptidoglycan cross-linking.
• Single Agent IV Antibiotic Therapy - MSSA · West Virginia University · Infectious Disease
  Single-agent intravenous antibiotic therapy targets and kills methicillin-susceptible Staphylococcus aureus (MSSA) by inhibiting bacterial cell wall synthesis.

Phase 3 pipeline (6)

• Benzyl penicillin · KEMRI-Wellcome Trust Collaborative Research Program · Infectious Disease
  Benzyl penicillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins and blocking peptidoglycan cross-linking.
• Usual antibiotic treatment · Assistance Publique - Hôpitaux de Paris · Infectious disease
  This drug inhibits bacterial cell wall synthesis.
• Piperacillin/Tazobactam & Amoxicillin/Clavulanic acid · Bayer · Infectious Diseases
  Piperacillin/Tazobactam is a beta-lactam antibiotic that inhibits bacterial cell wall synthesis, while Amoxicillin/Clavulanic acid is a beta-lactam antibiotic that inhibits bacterial cell wall synthesis and is protected from beta-lactamase degradation by Clavulanic acid.
• cefepime/AAI101 combination · Allecra · Infectious Diseases
  Cefepime/AAI101 combination is a beta-lactam antibiotic that inhibits bacterial cell wall synthesis.
• Standard Antibiotics treatment duration · University of Oxford · Infectious diseases
  Standard antibiotics target and kill bacteria by inhibiting their cell wall synthesis or interfering with their protein synthesis.
• Pivmecillinam hydrochloride tablets · Benova (Tianjin) Innovative medicine Research Co., Ltd. · Infectious diseases
  Pivmecillinam hydrochloride is a beta-lactam antibiotic that inhibits bacterial cell wall synthesis.

Phase 2 pipeline (1)

• Beta Lactam Antibiotics · Esraa Salah Mohamed Abdallah Eladl · Infectious Disease
  Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.

Phase 1 pipeline (2)

• Amoxicillin - high dose dual therapy · Unidade Local de Saúde do Alto Ave, EPE · Infectious Disease
  Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.
• Amoxicillin healing phase · Belén Retamal-Valdes · Infectious Disease
  Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins.