What drugs target Beta-1 and beta-2 adrenergic receptors?

13+ drugs target Beta-1 and beta-2 adrenergic receptors, including betablocker titration, Timolol 0.5% Ophthalmic Solution, Topical timolol maleate, topical Timolol maleate 0.5% eye drops, Timolol 0.25% Ophthalmic Solution.

Beta-1 and beta-2 adrenergic receptors — Drug Target

13 drugs 6 marketed 6 in Phase 3

All drugs that target Beta-1 and beta-2 adrenergic receptors — marketed and clinical-stage. Includes 7 drug classes acting on this target.

Drug classes

Beta-adrenergic antagonist · Beta-adrenergic antagonist (non-selective) · Beta-adrenergic antagonist (non-selective beta-blocker) · Non-selective beta-adrenergic antagonist (beta-blocker) · Beta-adrenergic receptor antagonist (non-selective beta-blocker) · Non-selective beta-adrenergic antagonist · Non-selective beta-blocker

Marketed (6)

betablocker titration · Policlinico Casilino ASL RMB · Beta-adrenergic antagonist · Cardiovascular
Beta-blockers inhibit the effects of catecholamines on beta-adrenergic receptors, reducing heart rate, contractility, and blood pressure.
Timolol 0.5% Ophthalmic Solution · University of California, Davis · Beta-adrenergic antagonist · Ophthalmology
Timolol is a non-selective beta-adrenergic receptor antagonist that reduces intraocular pressure by decreasing aqueous humor production in the eye.
Topical timolol maleate · Unity Health Toronto · Beta-adrenergic antagonist · Ophthalmology
Topical timolol maleate is a non-selective beta-adrenergic receptor antagonist that reduces intraocular pressure by decreasing aqueous humor production in the eye.
topical Timolol maleate 0.5% eye drops · Ain Shams University · Beta-adrenergic antagonist (non-selective) · Ophthalmology
Timolol maleate is a non-selective beta-adrenergic receptor antagonist that reduces intraocular pressure by decreasing aqueous humor production in the eye.
Timolol 0.25% Ophthalmic Solution · Keith G. LeBlanc, Jr, MD · Beta-adrenergic antagonist (non-selective beta-blocker) · Ophthalmology
Timolol is a non-selective beta-adrenergic receptor antagonist that reduces intraocular pressure by decreasing aqueous humor production in the eye.
oral Propranolol · Ahmed talaat ahmed aly · Non-selective beta-adrenergic antagonist (beta-blocker) · Cardiovascular
Propranolol is a non-selective beta-adrenergic receptor antagonist that blocks the effects of epinephrine and norepinephrine on the heart and blood vessels.

Phase 3 pipeline (6)

Carteolol long-acting ophthalmic solution · Otsuka Pharmaceutical Co., Ltd. · Beta-adrenergic receptor antagonist (non-selective beta-blocker) · Ophthalmology
Carteolol is a non-selective beta-adrenergic receptor antagonist that reduces intraocular pressure by decreasing aqueous humor production in the eye.
Active Comparator: Timolol 0.5% · Allergan · Non-selective beta-adrenergic antagonist · Ophthalmology
Timolol is a non-selective beta-adrenergic receptor antagonist that reduces intraocular pressure by decreasing aqueous humor production in the eye.
Comparator: timolol · Merck Sharp & Dohme LLC · Beta-adrenergic antagonist (non-selective beta-blocker) · Ophthalmology
Timolol is a non-selective beta-adrenergic receptor antagonist that reduces intraocular pressure by decreasing aqueous humor production in the eye.
Propranolol LA · MetroHealth Medical Center · Non-selective beta-adrenergic antagonist · Cardiovascular
Propranolol is a non-selective beta-adrenergic receptor antagonist that blocks the effects of epinephrine and norepinephrine on the heart and blood vessels.
Preservative-Free Timolol maleate · Merck Sharp & Dohme LLC · Non-selective beta-adrenergic antagonist · Ophthalmology
Timolol maleate is a non-selective beta-adrenergic receptor antagonist that reduces intraocular pressure by decreasing aqueous humor production in the eye.
carvedilol immediate release · CTI-1, LLC · Non-selective beta-blocker · Cardiovascular
Carvedilol immediate release is a beta-blocker that works by blocking the effects of the hormone epinephrine, also known as adrenaline, and by slowing the heart rate and reducing its workload.

Phase 2 pipeline (1)

Carvedilol extended release only · GlaxoSmithKline · Non-selective beta-blocker · Cardiovascular
Carvedilol extended release is a beta-blocker that works by blocking the effects of the hormone epinephrine, also known as adrenaline, and by slowing the heart rate and reducing its workload.