Last reviewed · How we verify

Carvedilol extended release only

GlaxoSmithKline · Phase 2 active Small molecule

Carvedilol extended release is a beta-blocker that works by blocking the effects of the hormone epinephrine, also known as adrenaline, and by slowing the heart rate and reducing its workload.

Carvedilol extended release is a beta-blocker that works by blocking the effects of the hormone epinephrine, also known as adrenaline, and by slowing the heart rate and reducing its workload. Used for Hypertension, Heart failure.

At a glance

Generic nameCarvedilol extended release only
SponsorGlaxoSmithKline
Drug classNon-selective beta-blocker
TargetBeta-1 and beta-2 adrenergic receptors
ModalitySmall molecule
Therapeutic areaCardiovascular
PhasePhase 2

Mechanism of action

Carvedilol extended release is a non-selective beta-blocker that also has alpha-1 adrenergic blocking activity. This allows it to reduce blood pressure and heart rate, while also reducing the workload on the heart.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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