AT1 receptor — Drug Target

All drugs that target AT1 receptor — marketed and clinical-stage. Includes 9 drug classes acting on this target.

Drug classes

Angiotensin II receptor antagonist · Angiotensin receptor blocker · Angiotensin 2 Receptor Blocker · Angiotensin receptor blockers (ARBs) · Angiotensin receptor blocker (ARB) · ARB (Angiotensin II receptor blocker) · angiotensin II receptor blocker · ACE inhibitor · Angiotensin II receptor blocker

Marketed (10)

• Alphintern® , tablet, Amoun, Egypt · Ain Shams University · Angiotensin II receptor antagonist · Cardiovascular
  Alphintern is an antihypertensive agent that works by blocking the action of angiotensin II at its receptor sites, thereby reducing blood pressure.
• Stop group · Asan Medical Center · Angiotensin receptor blocker · Cardiovascular
  This drug works by inhibiting the renin-angiotensin system.
• Edarbi · Arbor Pharms Ireland · Angiotensin 2 Receptor Blocker · Cardiovascular
  Azilsartan blocks angiotensin II's vasoconstrictor and aldosterone-secreting effects by selectively binding to the AT1 receptor.
• MIR · Rambam Health Care Campus · Angiotensin receptor blocker · Cardiovascular
  MIR is a medication that works by inhibiting the renin-angiotensin system.
• group C · Kaohsiung Medical University Chung-Ho Memorial Hospital · Angiotensin II receptor antagonist · Cardiovascular
  This drug works by inhibiting the renin-angiotensin system to lower blood pressure.
• The RP group · Beijing Tiantan Hospital · Angiotensin receptor blockers (ARBs) · Cardiovascular
  The RP group is a class of drugs that inhibit the renin-angiotensin system.
• The DR group · Beijing Tiantan Hospital · Angiotensin receptor blocker (ARB) · Cardiovascular
  The DR group is a class of drugs that targets the renin-angiotensin system to lower blood pressure and reduce the risk of cardiovascular events.
• A3 · Breath of Life International Pharma Ltd · Angiotensin receptor blocker · Cardiovascular
  A3 is a medication that works by inhibiting the renin-angiotensin system.
• Conversion schedule - Week 1 · St. Joseph's Hospital and Medical Center, Phoenix · Angiotensin II receptor antagonist · Cardiovascular
  This drug is used to treat hypertension by blocking the action of angiotensin II at its receptor.
• Cozaar · Merck & Co. · ARB (Angiotensin II receptor blocker) · Metabolic
  Losartan blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selectively binding to the AT1 receptor.

Phase 3 pipeline (8)

• AGT4, AGZ · Ahn-Gook Pharmaceuticals Co.,Ltd · angiotensin II receptor blocker · Cardiovascular
  AGT4 and AGZ are angiotensin II receptor blockers.
• Placebo to losartan potassium · Merck Sharp & Dohme LLC · Angiotensin II receptor antagonist · Cardiovascular
  Losartan potassium is an angiotensin II receptor antagonist that blocks the action of angiotensin II at its receptor in the blood vessels, causing them to relax and dilate, which lowers blood pressure and reduces the workload on the heart.
• Micardis Anlo · EMS · Angiotensin II receptor antagonist · Cardiovascular
  Micardis Anlo is an angiotensin II receptor antagonist that blocks the action of angiotensin II, a potent vasoconstrictor, to lower blood pressure.
• TA-7284 High · Tanabe Pharma Corporation · Angiotensin II receptor antagonist · Cardiovascular
  TA-7284 High is a drug that targets the renin-angiotensin system.
• Olmesartan medoxomil tablets high dose · Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company · Angiotensin II receptor antagonist · Cardiovascular
  Olmesartan medoxomil is an angiotensin II receptor antagonist that blocks the action of angiotensin II, a potent vasoconstrictor, thereby lowering blood pressure.
• Placebo Eprosartan mesylate · Abbott · Angiotensin II receptor antagonist · Cardiovascular
  Eprosartan mesylate is an angiotensin II receptor antagonist that blocks the action of angiotensin II, a potent vasoconstrictor, to lower blood pressure.
• Standard of Care IV antihypertensive · The Medicines Company · ACE inhibitor · Cardiovascular
  Blocks the action of angiotensin II at its receptor, leading to vasodilation and decreased blood pressure.
• AGT4 · Ahn-Gook Pharmaceuticals Co.,Ltd · Angiotensin II receptor antagonist · Cardiovascular
  AGT4 is an angiotensin II receptor antagonist.

Phase 2 pipeline (2)

• BR1400-A · Boryung Pharmaceutical Co., Ltd · Angiotensin II receptor antagonist · Cardiovascular
  BR1400-A is a small molecule that targets the renin-angiotensin system.
• Anti-hypertensive drug treatment · Universidade Gama Filho · Angiotensin II receptor blocker · Cardiovascular
  Blocks the action of angiotensin II at its receptor

Phase 1 pipeline (1)

• Active hypertension medical therapy · Verve Medical, Inc · Angiotensin II receptor antagonist · Cardiovascular
  Blocks the action of angiotensin II at the AT1 receptor