Last reviewed · How we verify
Levobupivacaine wound infusion
Levobupivacaine wound infusion is a Local anesthetic Small molecule drug developed by University of Genova. It is currently FDA-approved for Postoperative wound pain management via local infiltration.
Levobupivacaine is a local anesthetic that blocks sodium channels in nerve cell membranes to prevent pain signal transmission at the wound site.
Levobupivacaine is a local anesthetic that blocks sodium channels in nerve cell membranes to prevent pain signal transmission at the wound site. Used for Postoperative wound pain management via local infiltration.
At a glance
| Generic name | Levobupivacaine wound infusion |
|---|---|
| Sponsor | University of Genova |
| Drug class | Local anesthetic |
| Target | Voltage-gated sodium channels |
| Modality | Small molecule |
| Therapeutic area | Pain management / Anesthesia |
| Phase | FDA-approved |
Mechanism of action
Levobupivacaine is the S-enantiomer of bupivacaine, a long-acting amide local anesthetic. When infused into wound tissue, it penetrates nerve cell membranes and reversibly blocks voltage-gated sodium channels, preventing depolarization and propagation of action potentials. This results in local anesthesia and analgesia at the surgical wound site, reducing postoperative pain.
Approved indications
- Postoperative wound pain management via local infiltration
Common side effects
- Local tissue irritation
- Systemic toxicity (if absorbed in high concentrations)
- Allergic reaction
Key clinical trials
- Postoperative Analgesia With a Catheter Under the Erector Spinae Muscle for Videothoracoscopic Lung Surgery (NA)
- Impact of Thoracic Epidural Versus Serratus Anterior Plane Block Versus Erector Spinae Plane Block on Incidence of PTPS (NA)
- Local Continuous Wound Infusion of Anesthetics in the Management of Post-operative Pain After Total Hip Arthroplasty. (PHASE3)
- Levobupivacaine Prolonged Wound Infusion for Postoperative Pain Relief After Breast Surgery (PHASE4)
- Usage of Tramadol With Levobupivacaine for Pain Treatment After Cesarean Section (PHASE4)
- Epidural Versus Wound Infusion Plus Morphine Bolus in Open Abdominal Aortic Aneurysm Repair (PHASE4)
- Patient Controlled Epidural Analgesia Versus Local Infiltration Analgesia Following Knee Arthroplasty (NA)
- Levobupivacaine to the Surgical Wound Following Cesarean (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Levobupivacaine wound infusion CI brief — competitive landscape report
- Levobupivacaine wound infusion updates RSS · CI watch RSS
- University of Genova portfolio CI
Frequently asked questions about Levobupivacaine wound infusion
What is Levobupivacaine wound infusion?
How does Levobupivacaine wound infusion work?
What is Levobupivacaine wound infusion used for?
Who makes Levobupivacaine wound infusion?
What drug class is Levobupivacaine wound infusion in?
What development phase is Levobupivacaine wound infusion in?
What are the side effects of Levobupivacaine wound infusion?
What does Levobupivacaine wound infusion target?
Related
- Drug class: All Local anesthetic drugs
- Target: All drugs targeting Voltage-gated sodium channels
- Manufacturer: University of Genova — full pipeline
- Therapeutic area: All drugs in Pain management / Anesthesia
- Indication: Drugs for Postoperative wound pain management via local infiltration
- Compare: Levobupivacaine wound infusion vs similar drugs
- Pricing: Levobupivacaine wound infusion cost, discount & access