Analgesia Postoperatoria Mediante Catetere Perdurare e Analgesia Postoperatoria Mediante Infusione Continua Periferia Nell'Intervento Chirurgico Per Riparazione Chirurgica di Aneurismi Dell'Aorta Addominale: Tecniche a Confronto (APERIVIP)

NCT02677532 Phase 4 COMPLETED

The aim of the study is to determine wether continuous wound infusion with local anaesthetic plus a single dose intravenous morphine is non-inferior to postoperative analgesia provided with continuous thoracic epidural infusion of local anaesthetic plus opiate, in patients undergoing open abdominal aortic aneurism repair.

Details

Lead sponsor	University of Genova
Phase	Phase 4
Status	COMPLETED
Enrolment	51
Start date	2011-12
Completion	2014-01

Conditions

• Postoperative Pain

Interventions

• Paracetamol
• Levobupivacaine wound infiltration
• Levobupivacaine epidural bolus
• Sufentanil epidural bolus
• Morphine
• Epidural catheter placement
• Wound infusion catheters placement
• Levobupivacaine plus sufentanil epidural infusion
• Levobupivacaine wound infusion

Primary outcomes

• Average postoperative pain assessed with numeric rating scale (NRS) in the first 48 hours — Average of the NRS recorded at the different time-points (up to 48 hours after emergence from general anaesthesia)

Countries

Italy