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Intraoperative anesthetic strategy by Propofol
Intraoperative anesthetic strategy by Propofol is a GABA_A receptor agonist Small molecule drug developed by Assistance Publique - Hôpitaux de Paris. It is currently in Phase 2 development for General anesthesia, Sedation.
Propofol acts as a GABA_A receptor agonist.
Propofol acts as a GABA_A receptor agonist. Used for General anesthesia, Sedation.
At a glance
| Generic name | Intraoperative anesthetic strategy by Propofol |
|---|---|
| Sponsor | Assistance Publique - Hôpitaux de Paris |
| Drug class | GABA_A receptor agonist |
| Target | GABA_A receptor |
| Modality | Small molecule |
| Therapeutic area | Anesthesiology |
| Phase | Phase 2 |
Mechanism of action
Propofol binds to the GABA_A receptor, enhancing the effect of the neurotransmitter gamma-aminobutyric acid (GABA), leading to sedative, hypnotic, and amnestic effects.
Approved indications
- General anesthesia
- Sedation
Common side effects
- Respiratory depression
- Hypotension
- Bradycardia
Key clinical trials
- Desflurane vs. Propofol for Cardiac Anesthesia (PHASE3)
- Evaluation Of The Influence Of Anesthetic Interventions On The Evolution Of Hepatic Neoplastic Processes (NA)
- Opioid-Free Combined Anesthesia With Spontaneous Breathing for VATS (NA)
- Evaluating the Influence of the Strategy Intraoperative Anesthetic (Desflurane Versus Propofol) on Cognitive and Psychomotor Functions in Output Post Interventional Room Monitoring - COGNIDES (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Intraoperative anesthetic strategy by Propofol CI brief — competitive landscape report
- Intraoperative anesthetic strategy by Propofol updates RSS · CI watch RSS
- Assistance Publique - Hôpitaux de Paris portfolio CI
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Related
- Drug class: All GABA_A receptor agonist drugs
- Target: All drugs targeting GABA_A receptor
- Manufacturer: Assistance Publique - Hôpitaux de Paris — full pipeline
- Therapeutic area: All drugs in Anesthesiology
- Indication: Drugs for General anesthesia
- Indication: Drugs for Sedation
- Compare: Intraoperative anesthetic strategy by Propofol vs similar drugs
- Pricing: Intraoperative anesthetic strategy by Propofol cost, discount & access