Randomized Study Evaluating the Influence of the Strategy Intraoperative Anesthetic (Desflurane Versus Propofol) on Cognitive and Psychomotor Functions in Output Post Interventional Room Monitoring (Cognides)

NCT02036736 Phase 2 COMPLETED

The recovery of cognitive and psychomotor functions is best performed under anesthesia after desflurane when propofol in that obtaining a Aldrete score\> 8/10 output of the allowing SSPI. The principal objective is to compare the cognitive and psychomotor status of patients recovered an Aldrete score\> 8/10 according to the anesthetic agent (propofol or desflurane) using three tests (Stroop test, Digit Symbol Substitution task and a test of verbal memory (visual verbal learning test) made SSPI.

Details

Lead sponsor	Assistance Publique - Hôpitaux de Paris
Phase	Phase 2
Status	COMPLETED
Enrolment	60
Start date	2013-04
Completion	2014-12

Conditions

• Orthopedic Surgery
• Total Hip Prosthesis
• Total Knee Replacement

Interventions

• Intraoperative anesthetic strategy by Propofol
• Intraoperative anesthetic strategy by Desflurane

Primary outcomes

• Compare the cognitive and psychomotor status of patients recovered an Aldrete score> 8/10 according to the anesthetic agent (propofol or desflurane) — 1 day
  Compare the cognitive and psychomotor status of patients recovered an Aldrete score\> 8/10 according to the anesthetic agent (propofol or desflurane), using three tests (Stroop test, Digit Symbol Substitution Task and test verbal memory (visual verbal learning test) made room post-interventional monitoring The primary endpoint will be the average score of three tests in room post-interventional monitoring (Stroop test, Digit Symbol Substitution Task, Visual Verbal Learning Test) scores expressed in standard deviation

Countries

France