Who are Intraoperative anesthetic strategy by Propofol's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): SAGE-547, Sevoflurane intravenous anesthesia, Sevoflurane + Remifentanyl, Auris-Sedina, propofol (drug), topiramate, propranolol.

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Last reviewed 2026-05-17 · How we verify

Intraoperative anesthetic strategy by Propofol — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Intraoperative anesthetic strategy by Propofol (Intraoperative anesthetic strategy by Propofol) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: GABA_A receptor agonist. Area: Anesthesiology.

phase 2 GABA_A receptor agonist GABA_A receptor Anesthesiology Small molecule Live · refreshed every 30 min

Target snapshot

Intraoperative anesthetic strategy by Propofol (Intraoperative anesthetic strategy by Propofol) — Assistance Publique - Hôpitaux de Paris. Propofol acts as a GABA_A receptor agonist.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Intraoperative anesthetic strategy by Propofol TARGET	Intraoperative anesthetic strategy by Propofol	Assistance Publique - Hôpitaux de Paris	phase 2	GABA_A receptor agonist	GABA_A receptor
SAGE-547	SAGE-547	Supernus Pharmaceuticals, Inc.	phase 3	antisense oligonucleotide	GABA_A receptor alpha 1 subunit
Sevoflurane intravenous anesthesia	Sevoflurane intravenous anesthesia	The Cleveland Clinic	phase 3	Volatile anesthetic	GABA_A receptor
Sevoflurane + Remifentanyl	Sevoflurane + Remifentanyl	Azienda Ospedaliera San Gerardo di Monza	phase 3	General anesthetic and opioid analgesic	GABA_A receptor and opioid receptors
Auris-Sedina	Auris-Sedina	Laboratorios Osorio de Moraes Ltda.	phase 3	Benzodiazepine	GABA_A receptor
propofol (drug)	propofol (drug)	B. Braun Melsungen AG	phase 3	GABA receptor agonist	GABA_A receptor
topiramate, propranolol	topiramate, propranolol	Johnson & Johnson Pharmaceutical Research & Development, L.L.C.	phase 3	Anticonvulsant	Voltage-dependent sodium channels, GABA_A receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (GABA_A receptor agonist class)

Alkermes, Inc. · 1 drug in this class
Assistance Publique - Hôpitaux de Paris · 1 drug in this class
Centre Hospitalier Universitaire de Saint Etienne · 1 drug in this class
The Cleveland Clinic · 1 drug in this class
University Hospital, Clermont-Ferrand · 1 drug in this class
Xiaobo Yang, MD · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Intraoperative anesthetic strategy by Propofol — Competitive Intelligence Brief. https://druglandscape.com/ci/intraoperative-anesthetic-strategy-by-propofol. Accessed 2026-05-17.

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