Last reviewed · How we verify
Seborrheic Dermatitis
Approved treatments
- Zinc Pyrithione
Zinc Pyrithione works by inhibiting the activity of a specific potassium channel in the skin, which helps to reduce inflammation and prevent fungal growth. - Flucorticin
- Salonpas
- Allantol
- Aclovate
- Cordran · Aqua Pharms
- Cutivate · Teva Pharm
- Temovate · Fougera Pharms
- Benzamycin · Mayne Pharma
- Topicort · Taro
- Klaron · Merck & Co.
- Derma-Smoothe/Fs · Eurofarma
- Cloderm · Legacy Pharma
- Cortone
- Ultravate · Ranbaxy
Ultravate works by binding to the glucocorticoid receptor, triggering a cascade of anti-inflammatory effects that reduce skin inflammation. - Diprolene · Merck & Co.
Diprolene works by binding to the glucocorticoid receptor in the skin, which reduces inflammation and suppresses the immune system. - ammonia
- Verdeso · Padagis Us
- Betamethasone Valerate · Fougera Pharms Inc
- Decadron · Generic (originally Merck)
- Flonase · GSK (GlaxoSmithKline)
- Nasonex · University of Alberta
- Medrol · Generic (originally Upjohn/Pfizer)
Potent synthetic glucocorticoid with 5x hydrocortisone potency and minimal mineralocorticoid activity, used for severe inflammatory conditions. - Betamethasone 17-Benzoate
- Cortef · Generic (originally Merck/Upjohn)
- SULFUR · Poythress
- Rodinolone
- Flixotide · Mundipharma Research Limited
- Fluticason · Creighton University
- Climbazol
Climbazol works by blocking the action of an enzyme called Cytochrome P450 3A4. - Nizoral · Johnson & Johnson (Janssen)
- Lidex
- Halog · Sun Pharma
- Lac-Hydrin · Sun Pharma
- Dermatop · Bausch Health
- Elocon · Merck & Co.
Elocon works by binding to the progesterone receptor, which reduces inflammation and immune response in the body. - Clofuzid
- Psorcon · Pfizer
- Cyclocort · Astellas Pharma
- Selsun · Chattem
- Betametasone
Betamethasone works by binding to the glucocorticoid receptor, which then triggers a series of downstream effects that reduce inflammation and suppress the immune system. - Loprox · Bausch Health
- Cortisol · University of Zurich
- Prelone · Generic (originally Schering)
- Benoxyl · Aier School of Ophthalmology, Central South University
- Penlac · 9305-9954 Quebec Inc
- prednisolon · Hannover Medical School
- Methylprednisolon · Leiden University Medical Center
- MOMETASONE
12.1 Mechanism of Action Mometasone furoate nasal spray is a corticosteroid demonstrating potent anti-inflammatory properties. The precise mechanism of corticosteroid action on allergic rhinitis is not known. Corticosteroids have been shown to have a wide range of effects on multiple cell types (e.g., mast cells, eosinophils, neutrophils, macrophages, and lymphocytes) and mediators (e.g., histamine, eicosanoids, leukotrienes, and cytokines) involved in inflammation. In two clinical studies utilizing nasal antigen challenge, mometasone furoate nasal spray decreased some markers of the early- and late-phase allergic response. These observations included decreases (vs. placebo) in histamine and eosinophil cationic protein levels, and reductions (vs. baseline) in eosinophils, neutrophils, and epithelial cell adhesion proteins. The clinical significance of these findings is not known. The effect of mometasone furoate nasal spray on nasal mucosa following 12 months of treatment was examined in 46 patients with allergic rhinitis. There was no evidence of atrophy and there was a marked reduction in intraepithelial eosinophilia and inflammatory cell infiltration (e.g., eosinophils, lymphocytes, monocytes, neutrophils, and plasma cells).
Pipeline
- PF-07038124 · Pfizer Inc. — Phase 2
Competitive intelligence
For the full treatment-landscape CI brief — marketed leaders side-by-side, pipeline by phase, recent regulatory actions, sponsor landscape:
- Seborrheic Dermatitis patent landscape — cliff calendar, originator estates, attackable patents
- Seborrheic Dermatitis treatment landscape brief
- Seborrheic Dermatitis treatment updates RSS
Frequently asked questions about Seborrheic Dermatitis
What drugs treat Seborrheic Dermatitis?
Tracked treatments include Zinc Pyrithione, Flucorticin, Salonpas, Allantol, Aclovate, Cordran, Cutivate, Temovate.
What is the treatment for Seborrheic Dermatitis?
Standard treatment for Seborrheic Dermatitis includes Zinc Pyrithione, Flucorticin, Salonpas, Allantol, Aclovate. See the treatment landscape page for first-line, second-line and salvage options.
What new drugs are in development for Seborrheic Dermatitis?
1 pipeline drugs tracked. Top candidates: PF-07038124.
Related
- Treatment landscape: Seborrheic Dermatitis patent cliff · Seborrheic Dermatitis CI report
- Treatment: Zinc Pyrithione
- Treatment: Flucorticin
- Treatment: Salonpas
- Treatment: Allantol
- Treatment: Aclovate
- All diseases: Browse the disease index · Disease landscape hub
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing