Last reviewed 2026-04-20 · How we verify

Allantol (ALLANTOIN)

Allantoin, marketed under the brand name Allantol, is a topical agent primarily indicated for the treatment of skin itching, currently holding a position in the over-the-counter skincare market. Its key strength lies in its mechanism of action, which promotes skin hydration and reduces inflammation by increasing the water content of the skin. The primary risk to Allantol's market position is the expiration of its key composition patent in 2028, which could lead to increased competition from generic formulations.

At a glance

Approved indications

• Itching of skin
• Minor Skin Wound Pain
• Pityriasis simplex
• Psoriasis
• Seborrheic dermatitis
• Skin irritation

Common side effects

No common side effects on file.

Key clinical trials

• Efficacy and Safety Study to Evaluate SD-101 in Epidermolysis Bullosa (PHASE3)
• An Open Label Extension Safety Study to Evaluate SD-101 in Epidermolysis Bullosa (PHASE3)
• Temporary Inactivation of Strong Muscle Sensation to Improve Rehabilitation Interventions in SCI (PHASE1)
• Effect of Topical Agents With Various Antioxidant Containts on Photodamage Skin Induced (PHASE2)
• The Use of Arnica Montana in the Cicatrization of the Umbilical Cord
• Effectiveness and Safety of Topical Hyaluronic Acid of Different Molecular Weights in Xerotic Skin Treatment (PHASE3)
• Effect of Kangaroo Mother Care on Oxidative Stress and Bonding (NA)
• Elimination of Odor and Treatment of Malodorous Recalcitrant Wounds by Using Supraz and PRP-FG Versus Standard of Care (PHASE2,PHASE3)

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.