Discontinued drugs — metabolic
Drug development has roughly a 90% failure rate. This tracker catalogues compounds that were halted in clinical development or withdrawn after marketing, with the documented reason and the sponsor. Useful for understanding what's worked vs. what hasn't in a given disease, mechanism, or class.
- Chromium Tripicolinate · Metabolic
Chromium Picolinate works by facilitating the uptake of glucose into cells, potentially improving insulin sensitivity and glucose metabolism. - Galactopyranose · Metabolic · galactose
Galactose works by interacting with cellular receptors and enzymes to influence various biological pathways. - Inosital · Metabolic · inositol
Inosital works by influencing the metabolism of lipids in the body. - ALEGLITAZAR · Metabolic
Aleglitazar is being studied to see if it can lower cardiovascular risk and improve heart function in people with diabetes. - Tradjenta · EMS · Metabolic
- Metaclopramide · Institute of Liver and Biliary Sciences, India · Metabolic
- Januvia · Johns Hopkins University · Metabolic
- Livalo · Kowa Research Institute, Inc. · Metabolic
- Aminoglycosides · Methodist Health System · Metabolic
- ODM-108 Part III · Orion Corporation, Orion Pharma · Metabolic · Unknown — investigational small molecule
ODM-108 mechanism of action is not publicly disclosed; Phase 1 evaluation focused on safety and pharmacokinetics in healthy volunteers. - Growth Hormone Replacement Therapy · Pfizer Inc. · Metabolic · An observational study of patients who are commencing GH replacement as part of their routine NHS cl
An observational study of patients who are commencing GH replacement as part of their routine NHS cl - PF-07081532 · Pfizer Inc. · Metabolic · Experimental oral GLP-1 drug
- PF-07976016 · Pfizer Inc. · Metabolic · Taken once daily
- OLIMEL 7,6%E / PeriOLIMEL 2,5%E · RWTH Aachen University · Metabolic · Parenteral nutrition emulsion
Parenteral nutrition emulsion providing balanced amino acids, glucose, lipids, and electrolytes for intravenous metabolic support in patients unable to tolerate enteral feeding. - Colestimide · Tanabe Pharma Corporation · Metabolic · colestilan
Colestimide works by inhibiting the absorption of cholesterol and/or phosphorus in the intestines.