Novo Nordisk (NVO)
Quick facts
| Ticker | NVO (NYSE) |
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Marketed products
- Ozempic · Metabolic · revenue 27400
Semaglutide, a GLP-1 analogue, lowers blood glucose by stimulating insulin and inhibiting glucagon secretion in a glucose-dependent manner, and delays gastric emptying. - Tresiba · Metabolic · revenue 4500
Tresiba works by binding to the insulin receptor, mimicking the action of natural insulin to lower blood sugar levels. - Victoza · Metabolic · revenue 3200
- Novolog · Metabolic · revenue 2800
Novolog works by binding to the insulin receptor, triggering a cascade of cellular responses that lower blood glucose levels. - activated recombinant human factor VII
- Basal insulin analogues · Diabetes
Basal insulin analogues are long-acting insulin formulations that bind to insulin receptors to promote glucose uptake and utilization, providing steady background insulin coverage for blood glucose control. - BIAsp 30
- biphasic human insulin
- biphasic human insulin 30 · Diabetes
Biphasic human insulin 30 is a premixed insulin formulation that provides both rapid-acting and long-acting insulin coverage to regulate blood glucose levels in diabetes. - biphasic human insulin 50 · Diabetes
Biphasic human insulin 50 is a combination insulin product that provides both rapid-acting and long-acting insulin coverage to regulate blood glucose levels in diabetes. - biphasic insulin aspart · Diabetes
Biphasic insulin aspart is a rapid-acting insulin analog that binds to insulin receptors to facilitate glucose uptake and utilization in cells, with a biphasic formulation providing both immediate and intermediate insulin coverage. - biphasic insulin aspart 30 · Diabetes
Biphasic insulin aspart 30 is a premixed insulin that combines rapid-acting insulin aspart with intermediate-acting insulin to provide both immediate and sustained blood glucose control. - biphasic insulin aspart 50 · Diabetes
Biphasic insulin aspart 50 is a premixed insulin formulation that provides rapid-acting insulin aspart combined with intermediate-acting insulin to control blood glucose in diabetes. - Novothirteen · Metabolic
- Alhemo · Rare Disease
Alhemo works by blocking the activation of blood clotting factors to prevent excessive bleeding in people with hemophilia. - ALHEMO · Other
- DPP-4 inhibitors
- Eptacog Alfa · Rare Disease
- Eptacog alfa (NovoSeven) · Hematology
Eptacog alfa is a recombinant Factor VIIa that bypasses upstream coagulation defects by directly activating Factor X on the tissue factor pathway to initiate thrombin generation and hemostasis. - Esperoct · Other
- Exenatide-Bayetta
- factor VIII
- Feiba VH
- Fiasp® · Diabetes
Fiasp is a rapid-acting insulin analog that binds to the insulin receptor to facilitate glucose uptake and utilization in peripheral tissues. - glicazide · Other
- Glucobay®
- Glurenorm®
- human insulin · Diabetes
Human insulin binds to insulin receptors on cells to promote glucose uptake and utilization, lowering blood glucose levels. - human soluble insulin · Diabetes
Human soluble insulin binds to insulin receptors on cells to promote glucose uptake and utilization, lowering blood glucose levels. - IGlar U100 · Diabetes
IGlar U100 is a long-acting basal insulin that binds to insulin receptors to lower blood glucose by promoting glucose uptake and storage in peripheral tissues. - Insulin aspart (NovoRapid®) · Diabetes
Insulin aspart is a rapid-acting insulin analog that binds to insulin receptors on muscle and fat cells to promote glucose uptake and lower blood glucose levels. - Levemir · Metabolic
Levemir works by binding to the insulin receptor, triggering a response that lowers blood sugar levels. - Insulin glargine U100 · Diabetes
Insulin glargine is a long-acting basal insulin that binds to insulin receptors on cells to promote glucose uptake and reduce blood glucose levels. - Insulin-Levemir · Diabetes
Insulin detemir is a long-acting basal insulin that binds to the insulin receptor to facilitate glucose uptake and utilization in peripheral tissues while suppressing hepatic glucose production. - Insulin-Levemir and Exenatide-Bayetta
- insulin NPH · Diabetes
Insulin NPH is an intermediate-acting insulin that binds to insulin receptors on cells to promote glucose uptake and utilization, lowering blood glucose levels. - isophane human insulin · Diabetes
Isophane human insulin is an intermediate-acting insulin that binds to insulin receptors on cells to promote glucose uptake and utilization, lowering blood glucose levels. - Rivfloza · Metabolic
Nedosiran, a GalNAc-conjugated siRNA, binds to ASGPR on hepatocytes, degrades LDHA mRNA, reducing hepatic LDH and oxalate production. - Norditropin · Other
- NPH insulin · Diabetes
NPH insulin is a long-acting basal insulin that binds to insulin receptors on cells to promote glucose uptake and utilization, lowering blood glucose levels.
Phase 3 pipeline
- biphasic insulin aspart 70 · Diabetes
Biphasic insulin aspart 70 works by mimicking the body's natural insulin production to regulate blood sugar levels. - CagriSema · Endocrinology / Diabetes
CagriSema is a dual GLP-1/GCG receptor agonist that activates both glucagon-like peptide-1 and glucagon receptors to improve glycemic control and promote weight loss. - Etavopivat A · Hematology/Oncology
Etavopivat activates the Nrf2 (nuclear factor erythroid 2-related factor 2) pathway to increase fetal hemoglobin (HbF) production and reduce hemolysis in patients with sickle cell disease. - Etavopivat B · Hematology/Rare Blood Disorders
Etavopivat activates the pyruvate dehydrogenase kinase (PDK) inhibitor pathway to reduce hemolysis in sickle cell disease by modulating red blood cell metabolism. - Etavopivat C · Hematology/Rare Blood Disorders
Etavopivat activates the pyruvate dehydrogenase kinase (PDK) inhibitor pathway to reduce hemolysis in sickle cell disease by modulating red blood cell metabolism. - Faster-acting insulin aspart · Diabetes
Faster-acting insulin aspart is a rapid-acting insulin analog that binds to insulin receptors to facilitate glucose uptake and utilization in peripheral tissues. - Faster aspart · Diabetes
Faster aspart is a rapid-acting insulin analog that binds to the insulin receptor to facilitate glucose uptake and utilization in peripheral tissues. - IcoSema · Endocrinology
IcoSema is a dual GLP-1/GIP receptor agonist that activates both glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide receptors to improve glycemic control and promote weight loss. - insulin degludec/insulin aspart
- Insulin Glargine 100U/mL · Diabetes
Insulin glargine is a long-acting basal insulin that binds to insulin receptors on cells to promote glucose uptake and reduce blood glucose levels. - NNC0365-3769 (Mim8) · Diabetes
Mim8 is a glucagon-like peptide-1 (GLP-1) receptor agonist. - NNC0365-3769 (Mim8) PPX · Diabetes
Mim8 PPX is a glucagon-like peptide-1 (GLP-1) receptor agonist. - NNC0487-0111 · Diabetes, Obesity
NNC0487-0111 is a dual GLP-1/GIP receptor agonist that activates both glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide receptors to improve glycemic control and promote weight loss. - NNC6019-0001 · Diabetes
NNC6019-0001 is a glucagon receptor antagonist that blocks glucagon signaling to reduce hepatic glucose production and improve glycemic control. - oral anti-diabetic drug · Diabetes
Works by stimulating the release of insulin from the pancreas. - Placebo cagrilintide · Obesity / Metabolic disease
Cagrilintide is an amylin receptor agonist that slows gastric emptying and promotes satiety to reduce appetite and food intake. - Placebo (canagliflozin) · Diabetes
Canagliflozin inhibits sodium-glucose cotransporter 2 (SGLT2) in the kidney to increase urinary glucose excretion and lower blood glucose. - Placebo I (Semaglutide) · Diabetes, Obesity, Cardiovascular
Semaglutide is a GLP-1 receptor agonist that mimics glucagon-like peptide-1 to regulate blood glucose, reduce appetite, and promote weight loss. - Placebo II (Semaglutide) · Diabetes, Obesity
Semaglutide is a GLP-1 receptor agonist that mimics glucagon-like peptide-1 to regulate blood glucose, reduce appetite, and promote weight loss. - Placebo insulin icodec · Diabetes
Insulin icodec is a long-acting basal insulin analog that binds to the insulin receptor to regulate blood glucose by promoting glucose uptake and storage. - Placebo (Mim8)
Placebo (Mim8) is an inert control substance used in clinical trials to establish baseline efficacy and safety comparisons. - Placebo (ziltivekimab) · Cardiovascular
Ziltivekimab is a monoclonal antibody that inhibits interleukin-6 (IL-6) signaling to reduce inflammation. - repaglinide and metformin combination tablet · Diabetes
Repaglinide stimulates insulin secretion from the pancreas, while metformin decreases glucose production in the liver and increases insulin sensitivity. - rosiglitazone and metformin combination tablet · Diabetes
Rosiglitazone improves insulin sensitivity by activating peroxisome proliferator-activated receptor gamma (PPAR-γ), while metformin reduces hepatic glucose production and improves peripheral glucose uptake. - Semagludtide · Other
- Semaglutide B · Diabetes
Semaglutide B is a glucagon-like peptide-1 (GLP-1) receptor agonist that mimics the action of the natural hormone GLP-1 to regulate blood sugar levels. - Semaglutide J · Diabetes, Obesity
Semaglutide is a GLP-1 receptor agonist that mimics glucagon-like peptide-1 to regulate blood glucose, promote satiety, and slow gastric emptying. - Turoctocog alfa pegol (N8-GP) · Hematology
Turoctocog alfa pegol is a recombinant human coagulation factor VIII with extended half-life achieved through PEGylation, which replaces deficient clotting factor in hemophilia A patients. - Ziltivekimab B · Autoimmune diseases
Ziltivekimab B is an interleukin-1 beta (IL-1β) inhibitor. - Ziltivekimab C · Cardiovascular
Ziltivekimab is a monoclonal antibody that inhibits interleukin-6 (IL-6) signaling to reduce inflammation and cardiovascular risk.
Phase 2 pipeline
- EX1000
- HU - Hydroxyurea
- insulin 287
- insulin analogue
- NDec - oral decitabine-tetrahydrouridine
- NNC0090-2746
- NNC0174-0833
- NNC0194-0499
- NNC0480-0389
- NNC0487-0111 subcutanous
- NNC0519-0130
- NNC0662-0419
- NNC109-0012
- NNC126-0083
- Non-Vagifem® LDVE, Estradiol
- Norditropin® FlexPro®
- Norditropin® FlexPro® pen
- Norditropin NordiFlex®
- other injectable antidiabetic treatment regimens
- Refixia®
- Ryzodeg®
- Trizepatide · Other
Phase 1 pipeline
- 148-0287-A-4.2mM-cartridge
- Cagrilintide and Semaglutide
- Cagrilintide B
- CagriSema A
- Cocktail of 5 already approved drugs
- Decitabine-THU
- Genotropin Pen®
- I.v. NNC 0113-0987
- Insulin 320
- Insulin 338
- INV-347
- liraglutide [3H]
- liraglutide-depot
- Microgyn®
- N9-GP
- NC0194-0499
- NN1218
- NN1952
- NNC 0123-0000-0338
- NNC 0128-0000-2011
- NNC 0128-0000-2021
- NNC 0148-0000-0362
- NNC 0172-0000-2021
- NNC 55-0414
- NNC0113-0987
- NNC0113-2023
- NNC0113-6856
- NNC0113-6860
- NNC0113-6861
- NNC0113-6891
- NNC0114-0000-0005
- NNC0143-0406
- NNC0148-0287
- NNC0148-0287sema
- NNC0165-1562
- NNC0165-1875
- NNC0174-1213 A
- NNC0215-0384
- NNC0247-0829
- NNC0268-0965
Competitive intelligence
For the full portfolio CI brief — phase mix, recent regulatory actions, upcoming PDUFA dates, patent timeline, class-overlap with competitors: