Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

11 marketed · 25 in Phase 3

Quick facts

Marketed products

Abilify · Neuroscience
levofloxacin; metronidazole · Infectious Disease
This combination uses levofloxacin (a fluoroquinolone that inhibits bacterial DNA gyrase and topoisomerase IV) and metronidazole (a nitroimidazole that damages bacterial DNA) to provide broad-spectrum anaerobic and aerobic bacterial coverage.
norelgestromin + ethinyl estradiol · Contraception / Reproductive Health
Norelgestromin and ethinyl estradiol work together as a hormonal contraceptive by suppressing ovulation through inhibition of gonadotropin-releasing hormone (GnRH) and feedback inhibition of luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
Other atypical antipsychotic drugs
Paliperidone ER
Pentosan polysulfate sodium 100 mg
Risperidone high dose · Psychiatry/Neurology
Risperidone blocks dopamine D2 and serotonin 5-HT2A receptors in the brain to reduce psychotic symptoms and stabilize mood.
Risperidone low dose · Psychiatry
Risperidone blocks dopamine D2 and serotonin 5-HT2A receptors in the brain to reduce psychotic symptoms and stabilize mood.
risperidone, quetiapine
ULTRAM ER
Yondelis · Oncology

Phase 3 pipeline

Canagliflozin (JNJ-28431754) · Diabetes
Canagliflozin inhibits sodium-glucose cotransporter 2 (SGLT2) in the kidney, reducing reabsorption of glucose and promoting urinary glucose excretion to lower blood glucose levels.
CG 5503;tapentadol · Pain Management
Tapentadol is a mu-opioid receptor agonist and norepinephrine reuptake inhibitor that provides analgesia through dual mechanisms.
CG5503 · Diabetes
CG5503 is a small molecule that targets the SGLT2 receptor.
CG5503 IR; tapentadol · Pain Management
Tapentadol is a mu-opioid receptor agonist and norepinephrine reuptake inhibitor that provides analgesia through dual mechanisms of action.
doripenum · Other
Epoetin alfa 3 times weekly /once weekly · Hematology/Oncology
Epoetin alfa is a recombinant erythropoietin that stimulates red blood cell production by binding to erythropoietin receptors on bone marrow progenitor cells.
Epoetin alfa once every two weeks · Hematology
Epoetin alfa is a recombinant erythropoietin that stimulates red blood cell production by binding to erythropoietin receptors on bone marrow progenitor cells.
Epoetin alfa once weekly · Hematology
Epoetin alfa is a recombinant erythropoietin that stimulates red blood cell production by binding to erythropoietin receptors on bone marrow progenitor cells.
ER OROS Paliperidone · Psychiatry
Paliperidone is an atypical antipsychotic that blocks dopamine D2 and serotonin 5-HT2A receptors in the brain.
Extended-release galantamine hydrobromide · Neurology
Galantamine is a cholinesterase inhibitor that increases acetylcholine levels in the brain by blocking its breakdown, and also acts as an allosteric modulator of nicotinic receptors.
Gemcitabine with R115777 · Oncology
Gemcitabine is a nucleoside analog that inhibits DNA synthesis, while R115777 is a farnesyltransferase inhibitor that blocks Ras protein activation, together targeting cancer cell proliferation through complementary pathways.
levofloxacin; amoxicillin/clavulanate · Infectious diseases
Levofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, while amoxicillin/clavulanate inhibits bacterial cell wall synthesis.
levofloxacin, azithromycin, amoxicillin/clavulanate · Infectious Diseases
Levofloxacin, azithromycin, and amoxicillin/clavulanate inhibit bacterial growth through different mechanisms, targeting DNA gyrase, protein synthesis, and cell wall synthesis, respectively.
levofloxacin; imipenem/cilastitin
norelgestromin + ethinyl estradiol; mercilon · Women's Health
Norelgestromin and ethinyl estradiol are used to prevent pregnancy by suppressing ovulation and altering cervical mucus and the uterine lining.
norelgestromin + ethinyl estradiol; triphasil. · Women's Health
Norelgestromin and ethinyl estradiol work together to prevent ovulation and thicken cervical mucus to prevent sperm from reaching the egg.
Paliperidone ER OROS · Psychiatry
Paliperidone ER OROS is an atypical antipsychotic that works by blocking dopamine receptors in the brain.
Pancrease MT 10.5, or MT 21 · Gastroenterology
Pancrease MT is a pancreatic enzyme supplement used to treat exocrine pancreatic insufficiency.
Placebo for Pancrease MT 10.5 or MT 21 · Gastrointestinal
This is a placebo, meaning it has no active therapeutic effect.
Risperidone, oral tablets · Psychiatry
Risperidone is an atypical antipsychotic that acts as a dopamine D2 receptor antagonist and serotonin 5-HT2A receptor antagonist.
Tapentadol ER (CG5503) · Pain
Tapentadol ER is a mu-opioid receptor agonist and norepinephrine reuptake inhibitor.
Tipifarnib;Zarnestra; R115777 · Oncology
Tipifarnib is a farnesyltransferase inhibitor that blocks the farnesylation of Ras proteins, which are involved in cell signaling and proliferation.
Topiramate; Carbamazepine; Valproate · Neurology
Topiramate is an anticonvulsant that acts as a voltage-dependent sodium channel blocker, whereas Carbamazepine is a tricyclic compound that stabilizes inactivated sodium channels, and Valproate is a fatty acid with anticonvulsant properties.
topiramate, phenytoin · Neurology
Topiramate is an anticonvulsant that works by blocking voltage-dependent sodium channels, stabilizing neuronal membranes, and reducing the release of excitatory neurotransmitters.
topiramate, propranolol · Neurology
Topiramate is an anticonvulsant that blocks voltage-dependent sodium channels and enhances the activity of GABA at the GABA_A receptor.

Phase 2 pipeline

Becaplermin users · Dermatology
Stimulates wound healing by promoting the proliferation and differentiation of keratinocytes and fibroblasts
Current Domperidone · Gastrointestinal
Current Domperidone acts as a dopamine D2 receptor antagonist.
doxorubicin HCL liposome; bevacizumab; carboplatin
ET743
JNJ 40929837
JNJ16269110 · Diabetes
JNJ16269110 is a selective and potent antagonist of the human glucagon receptor.
JNJ39758979
R092670
R209130
R228060
R256918
Transdermal Contraceptive System
ZARNESTRA, tipifarnib, R115777

Phase 1 pipeline

Competitive intelligence

For the full portfolio CI brief — phase mix, recent regulatory actions, upcoming PDUFA dates, patent timeline, class-overlap with competitors: