Volatile anesthetic

This page covers all Volatile anesthetic drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting GABA-A receptor, NMDA receptor, GABA-A receptor, NMDA glutamate receptor, GABA_A receptor.

Targets

GABA-A receptor, NMDA receptor · GABA-A receptor, NMDA glutamate receptor · GABA_A receptor

Marketed (7)

• Volatile anesthetic · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Anesthesiology
  Volatile anesthetics depress central nervous system activity by enhancing inhibitory GABA receptor signaling and inhibiting excitatory NMDA receptor function, producing unconsciousness and anesthesia.
• Sevorane (sevoflurane, Abbott) · Medical University of Gdansk · Anesthesiology
  Sevoflurane is a volatile anesthetic that depresses the central nervous system by enhancing inhibitory GABA neurotransmission and inhibiting excitatory glutamate signaling.
• original sevoflurane · Asan Medical Center · Anesthesiology
  Sevoflurane is a volatile anesthetic that enhances inhibitory neurotransmission and suppresses excitatory neurotransmission in the central nervous system to produce anesthesia.
• Sevoflurane, Isoflurane, Desflurane · University Hospital, Basel, Switzerland · Anesthesiology
  These volatile anesthetics enhance inhibitory GABA receptor signaling and inhibit excitatory NMDA receptor function to produce general anesthesia.
• Isoflurane, Sevoflurane or Desflurane · King's College Hospital NHS Trust · Anesthesiology
  These volatile anesthetics enhance inhibitory GABA receptor signaling and inhibit excitatory NMDA receptor function to produce general anesthesia.
• Suprane (desflurane), Baxter · Medical University of Gdansk · Anesthesiology
  Desflurane is a volatile anesthetic that depresses the central nervous system by enhancing inhibitory GABA neurotransmission and inhibiting excitatory glutamate signaling.
• Isoflurane Volatile Liquid · Federal University of São Paulo · Anesthesiology
  Isoflurane is a volatile anesthetic that enhances inhibitory neurotransmission and suppresses excitatory signaling in the central nervous system to produce anesthesia.

Phase 3 pipeline (3)

• Inahled Isoflurane · Assistance Publique - Hôpitaux de Paris · Anesthesiology
  Inhaled isoflurane is a volatile anesthetic that enhances inhibitory neurotransmission and suppresses excitatory signaling in the central nervous system to produce anesthesia.
• Sevoflurane intravenous anesthesia · The Cleveland Clinic · Anesthesiology
  Sevoflurane acts as a general anesthetic by modulating the activity of the GABA_A receptor, leading to a decrease in neuronal excitability.
• Inhaled sedation with sevoflurane · University Hospital, Clermont-Ferrand · Anesthesia/Sedation
  Sevoflurane is a volatile anesthetic that depresses central nervous system activity by enhancing inhibitory GABA signaling and inhibiting excitatory glutamate signaling, producing sedation and anesthesia.