Proton pump inhibitor

This page covers all Proton pump inhibitor drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting H+/K+-ATPase (proton pump), H+/K+ ATPase, Potassium-transporting ATPase.

Targets

H+/K+-ATPase (proton pump) · H+/K+ ATPase · Potassium-transporting ATPase

Marketed (9)

• Proton pump inhibitor (PPI) · IBSA Institut Biochimique SA · Gastroenterology
  Proton pump inhibitors block the hydrogen/potassium ATPase enzyme in gastric parietal cells, reducing gastric acid secretion.
• Rabeprazole 40 mg · Pfizer · Gastroenterology
• Aciphex · Waylis · Metabolic
  Aciphex works by irreversibly inhibiting the potassium-transporting ATPase enzyme in the stomach lining, reducing acid production.
• Proton pump inhibitor · AVM Biotechnology Inc · Gastroenterology
  Proton pump inhibitors block the hydrogen/potassium ATPase enzyme in gastric parietal cells, reducing gastric acid secretion.
• Proton Pump Inhibitors (PPI) · Samsung Medical Center · Gastroenterology
  Proton pump inhibitors block the hydrogen/potassium ATPase pump in gastric parietal cells, reducing gastric acid secretion.
• PPI (proton pump inhibitor) · University of Bologna · Gastroenterology
  Proton pump inhibitors block the hydrogen/potassium ATPase enzyme in gastric parietal cells, reducing gastric acid secretion.
• PPI · Merck Sharp & Dohme LLC · Gastroenterology
  PPIs inhibit the proton pump (H+/K+-ATPase) in gastric parietal cells to reduce gastric acid secretion.
• NX · GBG Forschungs GmbH · Gastrointestinal
  Nexium works by reducing the amount of acid produced in the stomach.
• sequential versus triple · Jun-Won Chung · Gastroenterology
  Sequential versus triple therapy is used to treat Helicobacter pylori infections by combining antibiotics to eradicate the bacteria.

Phase 3 pipeline (4)

• Prilosec OTC™ Tablets · Bayer · Gastrointestinal
  Prilosec OTC works by reducing the amount of acid produced in the stomach.
• commercially available lansoprazole · Jason Lang, M.D., M.P.H. · Gastroenterology
  Lansoprazole is a proton pump inhibitor that reduces gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme in the gastric parietal cells.
• Vagitrol V · Janssen-Cilag, S.A. · Gastrointestinal
  Vagitrol V is a medication that works by inhibiting the action of a specific enzyme.
• Standard triple therapy · Samsung Medical Center · Gastroenterology
  This triple therapy combines medications to treat Helicobacter pylori infections by inhibiting bacterial growth and promoting eradication.

Phase 2 pipeline (2)

• Lansoprazole Triple Therapy · HK inno.N Corporation · Gastroenterology
  Inhibits the H+/K+ ATPase enzyme in the gastric parietal cells
• Esomeprazole sodium for injection · Shandong New Time Pharmaceutical Co., LTD · Gastroenterology
  Inhibits the H+/K+ ATPase enzyme