Last reviewed · How we verify

Prilosec OTC™ Tablets

Bayer · Phase 3 active Small molecule

Prilosec OTC works by reducing the amount of acid produced in the stomach.

Prilosec OTC works by reducing the amount of acid produced in the stomach. Used for Treatment of frequent heartburn occurring 2 or more days a week.

At a glance

Generic namePrilosec OTC™ Tablets
SponsorBayer
Drug classProton pump inhibitor
TargetH+/K+ ATPase
ModalitySmall molecule
Therapeutic areaGastrointestinal
PhasePhase 3

Mechanism of action

It does this by inhibiting the H+/K+ ATPase enzyme system at the secretory surface of the gastric parietal cell. This leads to a decrease in gastric acid secretion, which can help alleviate symptoms of acid reflux and heartburn.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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