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sequential versus triple
Sequential versus triple therapy is used to treat Helicobacter pylori infections by combining antibiotics to eradicate the bacteria.
Sequential versus triple therapy is used to treat Helicobacter pylori infections by combining antibiotics to eradicate the bacteria. Used for Treatment of Helicobacter pylori infections, Eradication of H. pylori in patients with peptic ulcer disease.
At a glance
| Generic name | sequential versus triple |
|---|---|
| Sponsor | Jun-Won Chung |
| Drug class | Proton pump inhibitor |
| Modality | Small molecule |
| Therapeutic area | Gastroenterology |
| Phase | FDA-approved |
Mechanism of action
Sequential therapy involves taking antibiotics in a specific order to minimize antibiotic resistance, while triple therapy involves taking three antibiotics simultaneously. Both approaches aim to eradicate Helicobacter pylori, a common cause of stomach ulcers and gastritis.
Approved indications
- Treatment of Helicobacter pylori infections
- Eradication of H. pylori in patients with peptic ulcer disease
Common side effects
- Diarrhea
- Nausea
- Abdominal pain
Key clinical trials
- Posaconazole Plus PD-1 Inhibitors and Chemotherapy vs PD-1 Inhibitors and Chemotherapy in Neoadjuvant Therapy for Triple Negative Breast Cancer (PHASE2)
- Susceptibility Testing Guided Versus Empirical Therapy for Refractory H. Pylori Infection (PHASE4)
- Susceptibility-Guided Sequential Therapy for Helicobacter Pylori Infection (NA)
- Sequential Therapy Versus Triple Therapy for Helicobacter Pylori Eradication: a Placebo-controlled Trial (PHASE2, PHASE3)
- Combination Chemotherapy in Treating Patients With Stage III or Stage IV Ovarian Epithelial Cancer or Primary Peritoneal Cancer (PHASE3)
- Sequential and Concurrent FOLFOXIRI/Bevacizumab Regimens Versus FOLFOX/Bevacizumab in First-Line Metastatic Colorectal Cancer (PHASE2)
- Sequential Therapy Versus Quadruple Therapy as Second Line Treatment After Failure of the Standard Triple Therapy for H Pylori Infection (PHASE3)
- Comparison of Conventional Triple Therapy Versus Sequential Therapy for H. Pylori in Peptic Ulcer Disease: Prospective Randomized Trial (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- sequential versus triple CI brief — competitive landscape report
- sequential versus triple updates RSS · CI watch RSS
- Jun-Won Chung portfolio CI