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Esomeprazole sodium for injection
Inhibits the H+/K+ ATPase enzyme
Inhibits the H+/K+ ATPase enzyme Used for Gastroesophageal reflux disease, Erosive esophagitis, Zollinger-Ellison syndrome.
At a glance
| Generic name | Esomeprazole sodium for injection |
|---|---|
| Sponsor | Shandong New Time Pharmaceutical Co., LTD |
| Drug class | Proton pump inhibitor |
| Target | H+/K+ ATPase |
| Modality | Small molecule |
| Therapeutic area | Gastroenterology |
| Phase | Phase 2 |
Mechanism of action
Esomeprazole sodium is a proton pump inhibitor that reduces gastric acid secretion by inhibiting the H+/K+ ATPase enzyme in the gastric parietal cells.
Approved indications
- Gastroesophageal reflux disease
- Erosive esophagitis
- Zollinger-Ellison syndrome
Common side effects
- Headache
- Diarrhea
- Nausea
Key clinical trials
- Esomeprazole Plus Sucralfate for Post-ESD Ulcer Healing (PHASE4)
- Phase II Clinical Study of Vonorasan Fumarate Injection in the Treatment of Peptic Ulcer Bleeding (PHASE2)
- A Phase I Study of LX22001 for Injection in Healthy Subjects (PHASE1)
- A Multi-center, Double-blinding, Parallel and Positive-controlled Phase III Clinical Trial for Efficacy and Safety Evaluation of Ilaprazole Sodium for Injection on Prevention of Stress Ulcer Bleeding (PHASE3)
- The Safety and Efficacy of the Enhanced Recovery After Surgery(ERAS)Applied on Cardiac Surgery With Cardiopulmonary Bypass (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |