Prostaglandin analog

This page covers all Prostaglandin analog drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Prostaglandin E1 receptor (EP receptor), Prostaglandin F (FP) receptor, Prostaglandin E receptors (EP1, EP2, EP3, EP4).

Targets

Prostaglandin E1 receptor (EP receptor) · Prostaglandin F (FP) receptor · Prostaglandin E receptors (EP1, EP2, EP3, EP4) · Prostaglandin F2-alpha receptor · Prostaglandin F receptor (FP receptor) · PGF2α receptor · Prostaglandin receptors (EP and FP receptors) · Prostaglandin receptor · FP receptor

Marketed (8)

• Misoprostol Pill · University of North Carolina, Chapel Hill · Gastroenterology; Obstetrics and Gynecology
  Misoprostol is a prostaglandin E1 analog that binds to prostaglandin receptors to increase gastric mucus production and reduce gastric acid secretion.
• Misoprostol Oral Tablet · Bnai Zion Medical Center · Gastroenterology; Obstetrics/Gynecology
  Misoprostol is a prostaglandin E1 analog that increases gastric mucus production and bicarbonate secretion while reducing gastric acid secretion.
• Misoprostol (Cytotec) · Wolfson Medical Center · Gastroenterology; Obstetrics
  Misoprostol is a prostaglandin E1 analog that increases gastric mucus production and bicarbonate secretion while reducing gastric acid secretion.
• LO2A eye drops · Ocuwize LTD · Ophthalmology
  LO2A eye drops reduce intraocular pressure by enhancing aqueous humor outflow through the trabecular meshwork and Schlemm's canal.
• Prostaglandin E2 (Prostin) · University Medical Centre Maribor · Obstetrics/Gynecology, Neonatology, Gastroenterology
  Prostaglandin E2 (PGE2) binds to prostaglandin E receptors (EP receptors) on cell surfaces to modulate inflammation, vasodilation, and smooth muscle contraction.
• Hemabate · Pfizer · Other
• Prostaglandin E2 · Shaare Zedek Medical Center · Multiple (Obstetrics, Gastroenterology, Rheumatology)
  Prostaglandin E2 (PGE2) binds to prostaglandin E receptors (EP1-EP4) on cell surfaces to modulate inflammation, smooth muscle contraction, and various physiological processes.
• Misoprostol-only medication abortion regimen · Ibis Reproductive Health · Reproductive Health
  Misoprostol is a prostaglandin analog that causes uterine contractions and cervical dilation to induce abortion.

Phase 3 pipeline (6)

• vehicle of bimatoprost solution 0.03 % · Allergan · Ophthalmology
  Bimatoprost is a prostaglandin analog that mimics the action of prostaglandin F2-alpha, leading to increased uveoscleral outflow and decreased intraocular pressure.
• Vizol S DIGI EYE eye drops · Jadran Galenski laboratorij d.d. · Ophthalmology
  Vizol S DIGI EYE eye drops are used to reduce intraocular pressure in patients with glaucoma.
• Vaginal prostaglandin · Ain Shams University · Obstetrics/Gynecology
  Vaginal prostaglandins stimulate uterine contractions and cervical ripening to induce labor or facilitate pregnancy termination.
• Misoprostol Alone · University of Pennsylvania · Obstetrics/Gynecology
  Misoprostol is a prostaglandin E1 analog that binds to prostaglandin receptors to promote uterine contractions and cervical ripening.
• Sham Bimatoprost SR · AbbVie · Ophthalmology
  Sham Bimatoprost SR is a prostaglandin analog that mimics the action of prostaglandin F2-alpha.
• bimatoprost formulation A solution · Allergan · Ophthalmology
  Bimatoprost is a prostaglandin analog that mimics the action of prostaglandin F2-alpha, leading to increased uveoscleral outflow and reduced intraocular pressure.

Phase 2 pipeline (2)

• Bimatoprost cutaneous solution 0.03% · Allergan · Ophthalmology
  Bimatoprost activates the prostaglandin F2 alpha receptor (FP receptor), leading to increased uveoscleral outflow of aqueous humor and reduced intraocular pressure.
• Bimatoprost Sustained Release Implant · AbbVie · Ophthalmology
  Bimatoprost Sustained Release Implant works by releasing bimatoprost, a prostaglandin analog, to lower intraocular pressure.