Prostaglandin F2-alpha receptor — Drug Target

All drugs that target Prostaglandin F2-alpha receptor — marketed and clinical-stage. Includes 4 drug classes acting on this target.

Drug classes

dinoprost · Prostaglandin Analog · Prostaglandin Analog [EPC] · Prostaglandin analog

Marketed (5)

• Enzaprost · Pfizer · dinoprost · Cardiovascular
• Hemabate · Pfizer · Prostaglandin Analog · Other
• Vyzulta · Bausch Health · Cardiovascular
  Vyzulta works by activating the Prostaglandin F2-alpha receptor, which increases the outflow of aqueous humor from the eye, thereby reducing intraocular pressure.
• Xalatan · Thea Pharma · Prostaglandin Analog [EPC] · Cardiovascular
  Xalatan works by increasing the outflow of fluid from the eye, reducing pressure.
• Travatan · Prostaglandin Analog [EPC] · Cardiovascular
  Travatan works by increasing the outflow of fluid from the eye to reduce pressure.

Phase 3 pipeline (2)

• bimatoprost formulation A solution · Allergan · Prostaglandin analog · Ophthalmology
  Bimatoprost is a prostaglandin analog that mimics the action of prostaglandin F2-alpha, leading to increased uveoscleral outflow and reduced intraocular pressure.
• vehicle of bimatoprost solution 0.03 % · Allergan · Prostaglandin analog · Ophthalmology
  Bimatoprost is a prostaglandin analog that mimics the action of prostaglandin F2-alpha, leading to increased uveoscleral outflow and decreased intraocular pressure.