Platinum-based chemotherapy agent

This page covers all Platinum-based chemotherapy agent drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting DNA, DNA (forms crosslinks).

Targets

DNA · DNA (forms crosslinks)

Marketed (5)

• Carboplatin or Cisplatin · Second Hospital of Shanxi Medical University · Oncology
  Carboplatin and cisplatin are platinum-based chemotherapy agents that bind to DNA and form cross-links, preventing DNA replication and triggering cancer cell death.
• Carboplatin Injection · Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · Oncology
  Carboplatin is a platinum-based chemotherapy agent that forms DNA crosslinks, preventing cancer cell replication and inducing apoptosis.
• carboplatin periocular injection · Sun Yat-sen University · Oncology
  Carboplatin is a platinum-based chemotherapy agent that forms DNA crosslinks to kill rapidly dividing cancer cells.
• Oxaliplatin (OXAL) · Memorial Sloan Kettering Cancer Center · Oncology
  Oxaliplatin is a platinum-based chemotherapy agent that forms DNA crosslinks to kill rapidly dividing cancer cells.
• Eloxatin · Yakult Honsha · Oncology
  Oxaliplatin forms platinum-DNA crosslinks that inhibit replication and transcription.

Phase 3 pipeline (29)

• Dicycloplatin (TP21) · Gao-jun Teng · Oncology
  Dicycloplatin is a platinum-based chemotherapy agent that forms DNA crosslinks to inhibit cancer cell proliferation.
• Carboplatin (adjuvant） · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Oncology
  Carboplatin is a platinum-based chemotherapy agent that forms DNA crosslinks to kill rapidly dividing cancer cells.
• Cisplatin for Injection / Carboplatin Injection · Shanghai Junshi Bioscience Co., Ltd. · Oncology
  Cisplatin and carboplatin are platinum-based chemotherapy agents that bind to DNA and cause cross-linking, leading to cell death.
• Oxaliplatin during radiotherapy · Universitätsmedizin Mannheim · Oncology
  Oxaliplatin is a platinum-based chemotherapy agent that forms DNA crosslinks to kill cancer cells, and when combined with radiotherapy, enhances radiation-induced cell death through synergistic DNA damage.
• Placebo , cisplatin · Jiangsu Simcere Pharmaceutical Co., Ltd. · Oncology
  Cisplatin is a platinum-based chemotherapy agent that forms DNA crosslinks to inhibit cancer cell replication and induce apoptosis.
• Cisplatin (or Carboplatin) · Biocad · Oncology
  Cisplatin and carboplatin are platinum-based chemotherapy agents that bind to DNA and form cross-links, preventing DNA replication and transcription to kill rapidly dividing cancer cells.
• Carboplatin for Injection · Jiangsu HengRui Medicine Co., Ltd. · Oncology
  Carboplatin is a platinum-based chemotherapy agent that forms DNA crosslinks, preventing cancer cell replication and inducing apoptosis.
• Cisplatin 1 · Sun Yat-sen University · Oncology
  Cisplatin is a platinum-based chemotherapy agent that forms DNA crosslinks, preventing DNA replication and transcription in cancer cells.
• Cisplatin for injection · Shanghai Guangsheng Biopharmaceutical Co., Ltd · Oncology
  Cisplatin is a platinum-based chemotherapy agent that forms DNA crosslinks, preventing DNA replication and transcription in cancer cells.
• Oxaliplatin injection · Akeso · Oncology
  Oxaliplatin is a platinum-based chemotherapy agent that forms DNA crosslinks to inhibit cancer cell replication and induce apoptosis.
• Cisplatin （neoadjuvant） · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Oncology
  Cisplatin is a platinum-based chemotherapy agent that forms DNA crosslinks, preventing DNA replication and triggering cancer cell death.
• Alternative medications: carboplatin · Universität des Saarlandes · Oncology
  Carboplatin is a platinum-based chemotherapy agent that forms DNA crosslinks to kill rapidly dividing cancer cells.
• Oxaliplatin Based Chemotherapy · Amgen · Oncology
  Oxaliplatin is a platinum-based chemotherapy agent that forms DNA crosslinks to kill rapidly dividing cancer cells.
• B: CBDCA and Radiotherapy · Japan Clinical Oncology Group · Oncology
  CBDCA (carboplatin) is a platinum-based chemotherapy agent that forms DNA crosslinks to kill cancer cells, used in combination with radiotherapy to enhance tumor control.
• Cisplatin (arm B) · Taiho Pharmaceutical Co., Ltd. · Oncology
  Cisplatin is a platinum-based chemotherapy agent that forms DNA adducts and crosslinks, preventing DNA replication and triggering cancer cell death.
• Carboplatin (neoadjuvant） · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Oncology
  Carboplatin is a platinum-based chemotherapy agent that forms DNA crosslinks to kill rapidly dividing cancer cells.
• Chemotherapy with platine · Intergroupe Francophone de Cancerologie Thoracique · Oncology
  Platinum-based chemotherapy agents form DNA crosslinks that prevent cancer cell replication and induce apoptosis.
• Cisplatin (as radiosensitizer) · Merck Sharp & Dohme LLC · Oncology
  Cisplatin acts as a radiosensitizer by forming DNA adducts that enhance the cytotoxic effects of ionizing radiation, making cancer cells more susceptible to radiation-induced damage.
• Oxaliplatin intra-arteriel · Federation Francophone de Cancerologie Digestive · Oncology
  Oxaliplatin is a platinum-based chemotherapy agent that forms DNA crosslinks to kill cancer cells, delivered directly into the hepatic artery to maximize local concentration in liver tumors.
• Cisplatin injection · Guangzhou Double Bioproducts Co., Ltd · Oncology
  Cisplatin is a platinum-based chemotherapy agent that forms DNA crosslinks, preventing DNA replication and transcription in cancer cells.
• Platinum-Based Drug · Chinese Academy of Medical Sciences · Oncology
  Platinum-based drugs form covalent crosslinks with DNA, preventing replication and transcription to induce cancer cell death.
• Platinum, investigator's choice · Merck Sharp & Dohme LLC · Oncology
  Platinum compounds form DNA-damaging adducts that cross-link DNA strands, triggering apoptosis in rapidly dividing cancer cells.
• Oxaliplatin intravenous · Federation Francophone de Cancerologie Digestive · Oncology
  Oxaliplatin is a platinum-based chemotherapy agent that forms DNA crosslinks to inhibit cancer cell replication and induce apoptosis.
• Carboplatin (Induction) · Celgene · Oncology
  Carboplatin is a platinum-based chemotherapy agent that forms DNA crosslinks, preventing cancer cell replication and inducing cell death.
• Chemotherapy（carboplatin） · Shanghai Pulmonary Hospital, Shanghai, China · Oncology
  Carboplatin is a platinum-based chemotherapy agent that forms DNA crosslinks, preventing cancer cell replication and inducing apoptosis.
• Platinum-containing Salvage Chemotherapy · Kite, A Gilead Company · Oncology
  Platinum-containing chemotherapy agents work by forming DNA adducts that cross-link DNA strands, preventing replication and transcription, thereby inducing cancer cell death.
• Placebo , Oxaliplatin · University of Sao Paulo · Oncology
  Oxaliplatin is a platinum-based chemotherapy agent that forms DNA crosslinks to inhibit cancer cell replication.
• Cisplatin / Oxaliplatin · Cancer Trials Ireland · Oncology
  Cisplatin and oxaliplatin are platinum-based chemotherapy agents that bind to DNA and form cross-links, preventing DNA replication and triggering cancer cell death.
• weekly cisplatin · Korea Cancer Center Hospital · Oncology
  Weekly cisplatin is a platinum-based chemotherapy agent that forms DNA crosslinks to inhibit cancer cell replication and induce apoptosis.

Phase 2 pipeline (1)

• Carboplatin AUC 5 IVa · Gruppo Oncologico Italiano di Ricerca Clinica · Oncology
  Carboplatin is a platinum-based chemotherapy agent that forms DNA crosslinks, preventing cell replication and inducing apoptosis in cancer cells.