Osmotic diuretic

This page covers all Osmotic diuretic drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Glomerular filtrate osmolarity; intracellular water movement, Glomerular filtrate osmolarity; tubular reabsorption of water.

Targets

Glomerular filtrate osmolarity; intracellular water movement · Glomerular filtrate osmolarity; tubular reabsorption of water

Marketed (8)

• Mannitol 15% · Pfizer Inc.
  Osmotic diuretic that elevates glomerular filtrate osmolarity to inhibit tubular water reabsorption.
• Aridol Kit · Baxter
  Osmotic diuretic that elevates glomerular filtrate osmolarity to inhibit tubular water reabsorption.
• mannitol 20% intravenous fluid · Ain Shams University · Neurology, Ophthalmology, Critical Care
  Mannitol is an osmotic diuretic that draws fluid from tissues into the intravascular space and increases urine output to reduce intracranial and intraocular pressure.
• i.v. mannitol · University Hospital, Saarland · Neurology, Ophthalmology
  Mannitol is an osmotic diuretic that draws fluid from tissues into the intravascular space and increases urine output to reduce intracranial and intraocular pressure.
• Aridol Kit · Baxter
  Osmotic diuretic that elevates glomerular filtrate osmolarity to inhibit tubular water reabsorption.
• Aridol Kit · Baxter
  Osmotic diuretic that elevates glomerular filtrate osmolarity to inhibit tubular water reabsorption.
• variation of mannitol dose · University Hospital, Grenoble · Neurology, Ophthalmology, Critical Care
  Mannitol is an osmotic diuretic that draws fluid into the renal tubules and bloodstream to reduce intracranial pressure and promote diuresis.
• Mannitol · Baxter · Cardiovascular
  Osmotic diuretic that elevates glomerular filtrate osmolarity to inhibit tubular water reabsorption.

Phase 3 pipeline (2)

• Glycerol "OBA" · University of Aarhus · Neurology
  Glycerol acts as an osmotic agent that draws fluid into the intracellular and extracellular spaces, reducing intracranial pressure and edema.
• Mannitol 20% Infusion · Centre Hospitalier Universitaire de Besancon · Neurology
  Mannitol is an osmotic diuretic that draws fluid from tissues into the intravascular space and increases urine output to reduce intracranial pressure and cerebral edema.

Phase 2 pipeline (1)

• D-Mannitol · Thiogenesis Therapeutics, Inc. · Neurology
  D-Mannitol is an osmotic agent that draws fluid into the intracellular space to reduce intracranial pressure and improve cellular hydration.