Non-opioid analgesic

This page covers all Non-opioid analgesic drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting COX, COX-2, COX-1 and COX-3.

Targets

COX · COX-2 · COX-1 and COX-3

Phase 3 pipeline (2)

• Non Opioid Analgesics · Muhammad Rahman Efendi Nasution · Pain Management
  Non-opioid analgesics reduce pain by inhibiting cyclooxygenase enzymes or other pain signaling pathways without activating opioid receptors.
• Test acetaminophen · Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division · Pain relief
  Acetaminophen works by inhibiting the production of prostaglandins, which are chemicals that cause pain and fever.

Phase 2 pipeline (3)

• Post-Op acetaminophen · Nevakar, Inc. · Pain management
  Centrally acting analgesic
• Paracetamol hot drink · GlaxoSmithKline · Pain management
  Paracetamol acts as an inhibitor of COX-2 enzyme.
• Acetaminophen Alone · Allodynic Therapeutics, Inc · Pain Management
  Inhibits cyclooxygenase enzymes