Last reviewed · How we verify
Acetaminophen Alone
Inhibits cyclooxygenase enzymes
Inhibits cyclooxygenase enzymes Used for Pain relief, Fever reduction.
At a glance
| Generic name | Acetaminophen Alone |
|---|---|
| Sponsor | Allodynic Therapeutics, Inc |
| Drug class | Non-opioid analgesic |
| Target | COX-1 and COX-3 |
| Modality | Small molecule |
| Therapeutic area | Pain Management |
| Phase | Phase 2 |
Mechanism of action
Acetaminophen works by inhibiting the enzymes cyclooxygenase-1 and cyclooxygenase-3, which are involved in the production of prostaglandins, leading to reduced pain and fever.
Approved indications
- Pain relief
- Fever reduction
Common side effects
- Hepatotoxicity
- Nausea
- Vomiting
Key clinical trials
- A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032) (PHASE3)
- A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021) (PHASE3)
- Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone in Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥ 50% (MK-2870-007) (PHASE3)
- Jaw Muscle Pain Post Wisdom Molar Surgery (PHASE2)
- Opioid Free and Opioid Based Anesthesia in Elective Lumbar Spine Surgery
- Dual-Target CAR-NK Cells for Advanced Breast Cancer (HER2+ and TNBC) (PHASE1, PHASE2)
- Durvalumab and Vicineum in Subjects With High-Grade Non-Muscle-Invasive Bladder Cancer Previously Treated With Bacillus Calmette-Guerin (BCG) (PHASE1)
- A Research Study Looking Into the Effect of NNC0519-0130 on Blood Levels of a Birth Control Pill and Emptying of the Stomach in Women After Menopause (PHASE1)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Acetaminophen Alone CI brief — competitive landscape report
- Acetaminophen Alone updates RSS · CI watch RSS
- Allodynic Therapeutics, Inc portfolio CI