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Test acetaminophen
Acetaminophen works by inhibiting the production of prostaglandins, which are chemicals that cause pain and fever.
Acetaminophen works by inhibiting the production of prostaglandins, which are chemicals that cause pain and fever. Used for Relief of mild to moderate pain, Reduction of fever.
At a glance
| Generic name | Test acetaminophen |
|---|---|
| Also known as | Test ACM |
| Sponsor | Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division |
| Drug class | Non-opioid analgesic |
| Target | COX |
| Modality | Small molecule |
| Therapeutic area | Pain relief |
| Phase | Phase 3 |
Mechanism of action
It does this by irreversibly inhibiting the enzyme cyclooxygenase (COX), which is responsible for converting arachidonic acid into prostaglandins. This results in a decrease in the production of prostaglandins, leading to a reduction in pain and fever.
Approved indications
- Relief of mild to moderate pain
- Reduction of fever
Common side effects
- Hepatotoxicity
- Nausea
- Vomiting
- Abdominal pain
Key clinical trials
- Durvalumab and Vicineum in Subjects With High-Grade Non-Muscle-Invasive Bladder Cancer Previously Treated With Bacillus Calmette-Guerin (BCG) (PHASE1)
- Open-label Placebo (COLP) for Pain in Adolescent Idiopathic Scoliosis (AIS) Surgery+Surgical Treatment of Idiopathic Scoliosis (NA)
- E7 TCR T Cells for Human Papillomavirus-Associated Cancers (PHASE1, PHASE2)
- Helping Osteoarthritis Patients to Walk With NSAID (PHASE4)
- The Effects of Preemptive Multimodal Analgesic on Endodontic Pain Following Root Canal Therapy. (EARLY_PHASE1)
- 131I-Omburtamab, in Recurrent Medulloblastoma and Ependymoma (PHASE2)
- The Effect of Single Lung Ventilation Duration and Intraoperative Brain Oxygenation on Cognitive Function and Postoperative Pain in Geriatric Patients
- CYP2D6 Genotype-guided Management of Opioid Analgesics in Patients Undergoing Elective Ventral Hernia Repairs (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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