What are Nicotine replacement therapy drugs?

Nicotine replacement therapy drugs are pharmacologic agents that share a common mechanism (typically targeting Nicotinic acetylcholine receptors). 7 are currently marketed, with 3 more in clinical development.

What are the marketed Nicotine replacement therapy drugs?

Marketed Nicotine replacement therapy drugs include Mailed nicotine replacement therapy, nicotine patch, labeled use, Pre-Quit Nicotine Gum, Nicotine Mini, Nicotine Polacrilex Gum (2 mg), Nicoderm patch first, then Aveva patch.

Nicotine replacement therapy

7 marketed 3 in Phase 3

This page covers all Nicotine replacement therapy drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Nicotinic acetylcholine receptors.

Targets

Nicotinic acetylcholine receptors

Marketed (7)

Mailed nicotine replacement therapy · Massachusetts General Hospital · Smoking Cessation / Addiction Medicine
Nicotine replacement therapy delivered by mail provides nicotine to reduce withdrawal symptoms and cravings during smoking cessation.
nicotine patch, labeled use · University of Vermont · Gastroenterology
Pre-Quit Nicotine Gum · University of Wisconsin, Madison · Smoking Cessation / Addiction Medicine
Pre-Quit Nicotine Gum delivers nicotine orally to reduce withdrawal symptoms and cravings during smoking cessation.
Nicotine Mini · University of Wisconsin, Madison · Smoking Cessation / Addiction Medicine
Nicotine Mini is a nicotine replacement therapy product that delivers nicotine through a small, discrete oral form to reduce cravings and withdrawal symptoms in smokers attempting to quit.
Nicotine Polacrilex Gum (2 mg) · University of Hawaii · Smoking Cessation / Addiction Medicine
Nicotine binds to nicotinic acetylcholine receptors in the brain to reduce cravings and withdrawal symptoms during smoking cessation.
Nicoderm patch first, then Aveva patch · University of Maryland, Baltimore · Addiction Medicine / Smoking Cessation
A sequential nicotine replacement therapy regimen using transdermal patches to deliver nicotine and support smoking cessation.
Transdermal Nicoderm patch · Ottawa Heart Institute Research Corporation · Smoking Cessation / Addiction Medicine
Nicotine delivered transdermally binds to nicotinic acetylcholine receptors in the brain, providing nicotine replacement to reduce cravings and withdrawal symptoms during smoking cessation.

Phase 3 pipeline (3)

Nicotine Lozenges · GlaxoSmithKline · Addiction
Nicotine lozenges work by releasing nicotine into the bloodstream to help manage withdrawal symptoms and cravings associated with smoking cessation.
Nicotine Replacement Therapy Agent - Lozenges · NYU Langone Health · Addiction
Lozenges release nicotine into the bloodstream to help manage withdrawal symptoms and cravings.
Nicotine replacement therapy - nicotine lozenge · Iowa City Veterans Affairs Medical Center · Addiction
Nicotine replacement therapy lozenges work by releasing nicotine into the bloodstream to help manage withdrawal symptoms and cravings.