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Nicotine replacement therapy - nicotine lozenge
Nicotine replacement therapy lozenges work by releasing nicotine into the bloodstream to help manage withdrawal symptoms and cravings.
Nicotine replacement therapy lozenges work by releasing nicotine into the bloodstream to help manage withdrawal symptoms and cravings. Used for Smoking cessation.
At a glance
| Generic name | Nicotine replacement therapy - nicotine lozenge |
|---|---|
| Also known as | Nicotine polacrilix, Nicotine lozenge |
| Sponsor | Iowa City Veterans Affairs Medical Center |
| Drug class | Nicotine replacement therapy |
| Modality | Small molecule |
| Therapeutic area | Addiction |
| Phase | Phase 3 |
Mechanism of action
Nicotine replacement therapy lozenges are designed to provide a controlled amount of nicotine to the body, helping to alleviate withdrawal symptoms and cravings associated with nicotine addiction. This can help individuals gradually reduce their nicotine intake and eventually quit smoking.
Approved indications
- Smoking cessation
Common side effects
- Hiccups
- Mouth or throat irritation
- Nausea
- Vomiting
- Dizziness
- Headache
Key clinical trials
- Smoking Cessation and Menstrual Cycle Phase (PHASE4)
- Cytisine vs Nicotine Replacement Therapy (NA)
- ACT Lung Health Intervention: Phase Two (NA)
- iCanQuit Smoking Cessation Among Hispanic Adults (PHASE3)
- Varenicline for Smoking Reduction in Veterans Not Ready To Quit (PHASE4)
- Auricular Stimulation for Nicotine Withdrawal in Psychiatric Inpatients (NA)
- E-Cigarettes for Harm Reduction in Smokers With Opioid Use Disorder (PHASE2)
- Mobile Contingency Management for Smoking Cessation (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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