What are Microtubule Inhibitor drugs?

Microtubule Inhibitor drugs are pharmacologic agents that share a common mechanism (typically targeting Tubulin beta). 4 are currently marketed, with 7 more in clinical development.

What are the marketed Microtubule Inhibitor drugs?

Marketed Microtubule Inhibitor drugs include Halaven, Taxol, Jevtana Kit, Ixempra Kit.

Microtubule Inhibitor

4 marketed 7 in Phase 3

This page covers all Microtubule Inhibitor drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Tubulin beta, Tubulin beta-3 chain, Apoptosis regulator Bcl-2.

Targets

Tubulin beta · Tubulin beta-3 chain · Apoptosis regulator Bcl-2 · Beta-tubulin · Tubulin (microtubule dynamics) · Microtubules (β-tubulin) · Tubulin · Microtubules · Tubulin / Microtubules

Marketed (4)

Halaven · Eisai · Oncology · 400
Halaven works by binding to tubulin beta, disrupting microtubule dynamics and leading to cell death.
Taxol · Pfizer · Oncology · 368
Jevtana Kit · Accord Hlthcare · Oncology · 300
Cabazitaxel works by binding to tubulin beta, disrupting microtubule formation and preventing cancer cell division.
Ixempra Kit · R-Pharm Us Llc · Oncology
Ixempra Kit works by disrupting cell division, preventing cancer cells from growing and multiplying.

Phase 3 pipeline (7)

NK105 · Nippon Kayaku Co., Ltd. · Oncology
NK105 is a nanosomal formulation of paclitaxel, a microtubule inhibitor.
Eribulin mesylate injection · Jiangsu Alphamab Biopharmaceuticals Co., Ltd · Oncology
Eribulin mesylate is a microtubule dynamics inhibitor that binds to tubulin and suppresses microtubule growth, leading to cell cycle arrest and apoptosis in cancer cells.
Eribulin standard regimen · Ma Fei，MD · Oncology
Eribulin is a microtubule dynamics inhibitor that binds to tubulin and suppresses microtubule growth, leading to cell cycle arrest and apoptosis in cancer cells.
E7389 (Eribulin Mesylate) · Eisai Co., Ltd. · Oncology
Eribulin is a microtubule dynamics inhibitor that suppresses microtubule growth and induces apoptosis in cancer cells.
SHR-1316、Chemotherapeutic · Jiangsu HengRui Medicine Co., Ltd. · Oncology
SHR-1316 is a chemotherapeutic agent that inhibits tubulin polymerization to disrupt microtubule dynamics and induce cancer cell death.
Paclitaxel, Docetaxel, Irinotecan · Shanghai Hengrui Pharmaceutical Co., Ltd. · Oncology
Paclitaxel, Docetaxel, and Irinotecan are microtubule inhibitors that work by stabilizing microtubules, thereby inhibiting cell division.
Eribulin biweekly regimen · Ma Fei，MD · Oncology
Eribulin is a microtubule dynamics inhibitor that binds to tubulin and disrupts microtubule formation, leading to cancer cell death.