Beta-tubulin — Drug Target

All drugs that target Beta-tubulin — marketed and clinical-stage. Includes 5 drug classes acting on this target.

Drug classes

Microtubule inhibitor / Anti-inflammatory agent · Taxane; microtubule stabilizer · Anthelmintic · Microtubule inhibitor · Taxane

Marketed (1)

• Colchicine Pill · Brigham and Women's Hospital · Microtubule inhibitor / Anti-inflammatory agent · Rheumatology / Immunology
  Colchicine inhibits microtubule polymerization by binding to tubulin, thereby suppressing inflammatory cell migration and reducing production of inflammatory mediators.

Phase 3 pipeline (3)

• Placebo, docetaxel · Akeso · Taxane; microtubule stabilizer · Oncology
  Docetaxel is a microtubule-stabilizing agent that prevents microtubule disassembly, leading to cell cycle arrest and apoptosis in cancer cells.
• similar placebo to mebendazole · Swiss Tropical & Public Health Institute · Anthelmintic · Infectious Diseases
  This drug works by inhibiting the action of a specific enzyme involved in the lifecycle of parasitic worms.
• NK105 · Nippon Kayaku Co., Ltd. · Microtubule inhibitor · Oncology
  NK105 is a nanosomal formulation of paclitaxel, a microtubule inhibitor.

Phase 2 pipeline (2)

• Induction Paclitaxel · Radiation Therapy Oncology Group · Taxane · Oncology
  Inhibits microtubule assembly by binding to tubulin
• DHA-paclitaxel · Theradex · Taxane · Oncology
  Paclitaxel binds to tubulin, inhibiting microtubule formation and cell division.