What are Taxane drugs?

Taxane drugs are pharmacologic agents that share a common mechanism (typically targeting Microtubules). 0 are currently marketed, with 24 more in clinical development.

Taxane

0 marketed 16 in Phase 3 6 in Phase 2 2 in Phase 1

This page covers all Taxane drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Microtubules, Beta-tubulin.

Targets

Microtubules · Beta-tubulin

Phase 3 pipeline (16)

SID530, Taxotere · SK Chemicals Co., Ltd. · Oncology
Taxotere works by inhibiting microtubule formation in the mitotic spindle, resulting in cell cycle arrest at the G2/M phase and apoptosis.
Paclitaxel only · Tata Memorial Hospital · Oncology
Paclitaxel works by inhibiting cell division, thereby preventing cancer cells from multiplying.
Paclitaxel Lipid Suspension · Jina Pharmaceuticals Inc. · Oncology
Paclitaxel works by inhibiting cell division, thereby preventing cancer cells from multiplying.
paclitaxel combined with platinum · Fourth Affiliated Hospital of Guangxi Medical University · Oncology
Paclitaxel works by inhibiting cell division, thereby preventing cancer cells from multiplying.
XRP6976 (Docetaxel/Taxotere) · Sanofi · Oncology
XRP6976 (Docetaxel/Taxotere) works by inhibiting microtubule dynamics, thereby inducing cell cycle arrest and apoptosis in cancer cells.
local intracoronary dosis of Paclitaxel · University Hospital Tuebingen · Oncology
Paclitaxel works by inhibiting cell division, thereby preventing cancer cells from multiplying.
Paclical® · Oasmia Pharmaceutical AB · Oncology
Paclical is a formulation of paclitaxel, a microtubule inhibitor that disrupts microtubule dynamics, leading to cell cycle arrest and apoptosis in cancer cells.
placebo plus paclitaxel · Biotech Pharmaceutical Co., Ltd. · Oncology
Paclitaxel works by inhibiting cell division, thereby preventing cancer cells from growing and spreading.
concurrent chemotherapy with docetaxel · Air Force Military Medical University, China · Oncology
Docetaxel works by inhibiting microtubule dynamics, thereby inducing apoptosis in cancer cells.
Paclitaxel dosing according to SmPC · Central European Society for Anticancer Drug Research · Oncology
Paclitaxel works by inhibiting cell division, thereby preventing cancer cells from multiplying.
chemoradiotherapy Paclitaxel · Shandong Cancer Hospital and Institute · Oncology
Paclitaxel works by inhibiting cell division, thereby preventing cancer cells from growing and dividing.
Taxotere (docetaxel) · Seagen Inc. · Oncology
Taxotere (docetaxel) works by inhibiting cell division, ultimately leading to cell death in rapidly dividing cancer cells.
Taxotere , Epirubicin · National Taiwan University Hospital · Oncology
Taxotere works by inhibiting microtubule formation in the mitotic spindle, resulting in cell cycle arrest at the G2/M phase, and ultimately inducing apoptosis in cancer cells.
Placebo + Paclitaxel · Chengdu Kanghong Biotech Co., Ltd. · Oncology
Paclitaxel works by inhibiting cell division, thereby preventing cancer cells from growing and dividing.
Paclitaxel based chemotherapy · Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Oncology
Paclitaxel works by inhibiting cell division, thereby preventing cancer cells from multiplying and spreading.
larotaxel (XRP9881) · Sanofi · Oncology
Larotaxel is a taxane dimer that inhibits microtubule dynamics, thereby inducing apoptosis in cancer cells.

Phase 2 pipeline (6)

Albumin-bound Paclitaxone · RemeGen Co., Ltd. · Oncology
Albumin binding enhances the solubility of paclitaxel, allowing for higher doses to be administered.
ARD6562, Docetaxel · Sanofi · Oncology
ARD6562, Docetaxel, is a microtubule inhibitor that disrupts cell division.
Docetaxel only · Samsung Medical Center · Oncology
Docetaxel is a microtubule inhibitor that binds to tubulin and prevents microtubule assembly.
Docetaxel Polymeric Micelles for Injection · Jiangsu Simcere Pharmaceutical Co., Ltd. · Oncology
Docetaxel inhibits microtubule dynamics by stabilizing microtubules and preventing their depolymerization.
DHA-paclitaxel · Theradex · Oncology
Paclitaxel binds to tubulin, inhibiting microtubule formation and cell division.
Induction Paclitaxel · Radiation Therapy Oncology Group · Oncology
Inhibits microtubule assembly by binding to tubulin

Phase 1 pipeline (2)

ABT-348 and docetaxel · AbbVie (prior sponsor, Abbott) · Oncology
Docetaxel is a microtubule inhibitor that works by stabilizing microtubules and preventing cell division.
AK112, nab-paclitaxel, gemcitabine · Akeso · Oncology
Inhibits microtubule dynamics by binding to tubulin, thereby inhibiting cell division