What are the marketed Local anesthetic with opioid analgesic combination drugs?

Marketed Local anesthetic with opioid analgesic combination drugs include Bupivacaine and Fentanyl, Bupivacaine-fentanyl elective group, Ropivacaine/Fentanyl, Levobupivacaine and Fentanyl.

Local anesthetic with opioid analgesic combination

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

4 marketed 1 in Phase 3

This page covers all Local anesthetic with opioid analgesic combination drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds, targeting Voltage-gated sodium channels (bupivacaine); mu-opioid receptor (fentanyl), Voltage-gated sodium channels (bupivacaine); mu opioid receptor (fentanyl), Voltage-gated sodium channels (ropivacaine); mu opioid receptor (fentanyl).

Targets

Voltage-gated sodium channels (bupivacaine); mu-opioid receptor (fentanyl) · Voltage-gated sodium channels (bupivacaine); mu opioid receptor (fentanyl) · Voltage-gated sodium channels (ropivacaine); mu opioid receptor (fentanyl) · Voltage-gated sodium channels; mu-opioid receptor · Voltage-gated sodium channels (ropivacaine); mu-opioid receptor (sufentanil)

Marketed (4)

Bupivacaine and Fentanyl · Bnai Zion Medical Center · Anesthesia and Pain Management
Bupivacaine blocks sodium channels to provide local anesthesia, while fentanyl activates opioid receptors to provide analgesia, together delivering regional anesthesia and pain relief.
Bupivacaine-fentanyl elective group · Conrad Arnfinn Bjørshol · Anesthesia and Pain Management
Bupivacaine is a local anesthetic that blocks sodium channels in nerve fibers, while fentanyl is an opioid agonist that binds to mu opioid receptors to provide analgesia, together delivering regional anesthesia and analgesia for elective procedures.
Ropivacaine/Fentanyl · National Institute for Tuberculosis and Lung Diseases, Poland · Anesthesia/Pain Management
Ropivacaine is a local anesthetic that blocks sodium channels in nerve membranes, while fentanyl is an opioid agonist that binds to mu opioid receptors to provide analgesia.
Levobupivacaine and Fentanyl · Hamad Medical Corporation · Anesthesia and Pain Management
Levobupivacaine blocks sodium channels to provide local anesthesia, while fentanyl activates opioid receptors to provide analgesia.

Phase 3 pipeline (1)

Naropin 0.1% cum sufentanil · Bent Gymoese Jorgensen · Anesthesia, Pain Management
Naropin (ropivacaine) is a local anesthetic that blocks sodium channels in nerve membranes, while sufentanil is an opioid agonist that enhances analgesia through mu-receptor activation.