Live biotherapeutic product (probiotic)

This page covers all Live biotherapeutic product (probiotic) drugs tracked by Drug Landscape: marketed products and active clinical-stage compounds.

Marketed (5)

• E. coli Nissle suspension · University of Hohenheim · Gastroenterology
  E. coli Nissle is a live biotherapeutic probiotic strain that colonizes the gut and modulates the intestinal microbiota and immune system to promote gastrointestinal health.
• INF108F probiotic · Massachusetts General Hospital · Gastroenterology / Immunology
  INF108F is a live biotherapeutic probiotic that modulates the gut microbiome to promote immune tolerance and reduce intestinal inflammation.
• Lactobacillus Crispatus M247 · Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Infectious Disease / Women's Health
  Lactobacillus crispatus M247 is a live biotherapeutic agent that restores and maintains a healthy vaginal microbiome by colonizing the vaginal tract with beneficial lactobacilli.
• lactobacillus LB · Hospital General de Mexico · Gastroenterology / Immunology
  Lactobacillus LB is a probiotic bacterium that modulates the gut microbiota and intestinal immune function to promote gastrointestinal health.
• Lactobacillus casei variety rhamnosus granules · Seoul National University Hospital · Gastroenterology / Immunology
  Lactobacillus casei variety rhamnosus is a probiotic bacterium that colonizes the gut and modulates the intestinal microbiota and immune system.

Phase 3 pipeline (13)

• Lactobacillus plantarum strain 299v · Children's Oncology Group · Oncology; Immunology
  Lactobacillus plantarum strain 299v is a probiotic bacterium that modulates the gut microbiome and enhances intestinal barrier function and immune tolerance.
• lactobacillus LS · Ain Shams University · Gastroenterology / Immunology
  Lactobacillus LS is a probiotic strain that modulates the gut microbiota and enhances intestinal barrier function and immune response.
• EcN-Suspension · Ardeypharm GmbH · Immunology / Gastroenterology
  EcN-Suspension is a live biotherapeutic containing engineered Escherichia coli Nissle 1917 designed to modulate the gut microbiome and immune system.
• Bifidobacterium animalis subsp. lactis · University of Sao Paulo · Gastroenterology / Immunology
  Bifidobacterium animalis subsp. lactis is a probiotic bacterium that modulates the gut microbiota and enhances intestinal barrier function and immune tolerance.
• MBK-01 · Mikrobiomik Healthcare Company S.L. · Immunology / Gastroenterology
  MBK-01 is a microbiome-based therapeutic that modulates the composition and function of the gut microbiota to restore immune homeostasis and reduce inflammation.
• Oxabact OC5 - Oxalobacter formigenes HC-1 · OxThera · Nephrology
  Oxabact OC5 is a live biotherapeutic product that works by colonizing the gut with Oxalobacter formigenes HC-1, which degrades oxalate, reducing its absorption and systemic levels.
• Bacillus Licheniformis · Asan Medical Center · Gastroenterology / Immunology
  Bacillus licheniformis is a probiotic bacterium that modulates the gut microbiome and immune system to promote health and treat disease.
• Lactobacillus brevis CD2 Lozenges · Next Gen Pharma India Pvt. Ltd. · Immunology / Infectious Disease
  Lactobacillus brevis CD2 is a probiotic lozenge that colonizes the oral and respiratory tract to modulate local and systemic immune responses.
• IBP-9414 · Infant Bacterial Therapeutics · Immunology / Infectious Disease / Pediatrics
  IBP-9414 is a live biotherapeutic product designed to restore beneficial bacterial populations in the infant microbiome.
• Lcr Regenerans · Probionov · Gastroenterology / Immunology
  Lcr Regenerans is a live biotherapeutic product designed to restore and regenerate the gut microbiota composition.
• VE303 · Vedanta Biosciences, Inc. · Gastroenterology
  VE303 is a live biotherapeutic product that modulates the gut microbiome to treat inflammatory bowel disease.
• Lactobacillus plantarum strain 299 · Children's Oncology Group · Oncology / Immunology
  Lactobacillus plantarum strain 299 is a probiotic bacterium that modulates the gut microbiome and intestinal barrier function to support immune homeostasis.
• RBX2660 · Rebiotix Inc. · Infectious Disease / Gastroenterology
  RBX2660 is a microbiota restoration therapy that repopulates the gut microbiome to treat recurrent Clostridioides difficile infection.

Patent intelligence

• live biotherapeutic product patent landscape — aggregated cliff calendar, attackable patents, originator estates